Oncobesity News Posts

‘Game changing’ fat jabs WON’T help you lose as much weight as you think, scientists discover
SO-CALLED “miracle” weight-loss jabs are far less effective in the real world than in clinical trials, a major study has revealed. The new findings could

AI-Designed GLP-1 Peptides from ImmunoPrecise Antibodies Surpass Semaglutide in Receptor Activation Studies
AUSTIN, Texas–(BUSINESS WIRE)—- $IPA #AI–ImmunoPrecise Antibodies Ltd. (NASDAQ: IPA), a leader in AI-powered drug discovery and biotherapeutics, today announced compelling in vitro results demonstrating that

The Vibrating Belt Machine
I heard the discourse between Laraine and Christopher last night on the Downsized and I came across this article in the Business Insider today, and

Medical experts warn ‘Big Food’ is fighting back against Ozempic with addictive items for sale
Some medical experts warn that as Ozempic helps overcome food addiction, the junk food industry is adapting with ultraprocessed foods designed to hijack brain reward systems.

Americans are obsessed with taking the ‘work’ out of working out
H. Armstrong Roberts/ClassicStock/Getty Images; BI Every generation has its own version of the vibrating belt machine — the ’50s-era contraption that promised to literally shake

Incretin‐based therapies for individuals with obesity and heart failure with mildly reduced or preserved ejection fraction: A systematic review and meta‐analysis of randomized controlled trials
Abstract Aims Obesity is a major risk factor for heart failure with mildly reduced or preserved ejection fraction (HFpEF). This meta-analysis of randomised clinical trials

Current treatment guidelines and glycated haemoglobin goals for type 2 diabetes: Which patients are most likely to benefit from fixed‐ratio basal insulin glucagon‐like peptide‐1 receptor agonist combinations?
Abstract Basal insulin and glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are available in two fixed-ratio combinations (FRCs) for the treatment of type 2 diabetes (T2D),

The weight loss drug Mounjaro has been approved to treat sleep apnoea. How does it work?
coldsnowstorm/Getty Images Last week, Australia’s Therapeutic Goods Administration (TGA) approved the weight-loss drug Mounjaro to treat sleep apnoea, a condition in which breathing stops and

Metsera Unveils First-in-Class Once-Monthly Amylin Candidate MET-233i’s Positive Phase 1 Results
Metsera, Inc. (NASDAQ:MTSR) is one of the 13 Biotech Stocks with Huge Upside Potential. Metsera, Inc. (NASDAQ:MTSR) reported encouraging Phase 1 results for MET-233i, its

LucyRx and Personify Health Partner to Offer Integrated GLP-1 and Weight Management Solution for Employers
What You Should Know: – LucyRx, an independent, next-generation pharmacy benefits manager (PBM), and Personify Health®, the company making healthier easier announced a strategic partnership

Deep Apple signs big Novo deal for cardiometabolic small molecules
Deep Apple Therapeutics Inc. could bring in as much as $812 million in a new collaboration and license deal with Novo Nordisk A/S. The total

McDonald’s downgraded on GLP-1 drug worries: Wall Street’s top analyst calls
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Lawmakers urge Trump administration to clamp down on illicit GLP-1 sales
A bipartisan group of congressional lawmakers is calling on the Trump administration to address the continued sale of illicit, compounded GLP-1 products, warning that consumers

Fatty Liver a Major Health Risk: Experts
Nonalcoholic fatty liver disease refers to a range of conditions in which fatty deposits occur in the liver. (Representational Image)Nonalcoholic fatty liver disease refers to

Study: Real-world results of GLP-1 drugs don’t match trials
Real-world results for blockbuster weight-loss meds like Ozempic, Wegovy and Zepbound aren’t as impressive as those promised by the drugs’ clinical trials, a new study

Can Mounjaro, Zepbound Help Lilly Maintain Dominance in Obesity Space?
Eli Lilly’s LLY key top-line drivers are its GLP-1 medicines, Mounjaro for type II diabetes and Zepbound for obesity. Both have witnessed rapid demand despite

Reality check: Unpacking the $150B GLP-1 market forecasts
Market expectations for GLP-1 agonists have been high for some time. But in the past year, sales forecasts have gone stratospheric. Last month, Morgan Stanley

Cleveland Clinic Research Finds Injectable Medications for Obesity Produce Smaller Weight Loss in A Real-World Setting, Compared to Randomized Clinical Trials – Cleveland Clinic Newsroom
Cleveland Clinic Research Finds Injectable Medications for Obesity Produce Smaller Weight Loss in A Real-World Setting, Compared to Randomized Clinical Trials Cleveland Clinic Newsroom Real-World Use

Use of GLP-1 RAs is associated with a 2-fold higher risk of Macular Degeneration
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Virta Health Survey Reveals Secret to Lasting Weight Loss After GLP-1s: Users Who Follow a Guided Off-ramp are 8x More Likely to Continue Losing Weight
DENVER–(BUSINESS WIRE)–Virta Health, a leader in diabetes reversal and sustainable weight loss with a nutrition-first approach, today released a report showing that people can maintain

Real-World Results For GLP-1 Drugs Underwhelm, Study Says
By Dennis Thompson HealthDay ReporterWEDNESDAY, June 11, 2025 (HealthDay News) — Real-world results for blockbuster weight-loss meds like Ozempic,…

Why Omada Health is resisting an AI takeover after its IPO
Omada Health’s president Wei-Li Shao and CEO Sean Duffy at the company’s June 6 IPO. Omada Health AI is taking over healthcare, but Omada Health

How to keep weight off after obesity drugs
Nature, Published online: 11 June 2025; doi:10.1038/d41586-025-01770-0 Options are emerging for the tens of millions of people who stop taking GLP-1 drugs because of side

Weight-Loss Drug ETFs Generate Skinnier Returns Than Expected
GLP-1 investors haven’t gained as much as expected from others’ losses. Since the FDA approved Wegovy, also known as semaglutide, as an injectactable treatment to help

‘Pharma is eating Big Food’s lunch…’ Lembas fights back with GLP-1 boosting peptide
Israeli foodtech startup Lembas has emerged from stealth with “GLP-1 Edge,” a bioactive peptide that triggers the production of GLP-1 and other gut hormones that

Novo Nordisk’s Canadian Mistake
This was an interesting interview with Richard Saynor, the head of Sandoz (which is now an independent generics company). That’s a part of the industry

Less Real-World GLP-1 Weight Loss; TROA Support; Rebuttal to Vitamin D Guidelines
(MedPage Today) — Researchers found that injectable GLP-1 receptor agonists for obesity tended to yield smaller reductions in weight in real-world settings versus what is

I Let This App Dictate My Workouts Based on My DNA – Was It Worth It?
I’ve done plenty of DNA tests to help me explore my heritage a little deeper (I’m a hodgepodge of Eastern European, in case you’re wondering).

Doctors Concerned By Massive Uptick In Teens Taking Ozempic
Teens are being prescribed Ozempic and similar drugs more than ever before — and some doctors are worried about what the trend could mean. In

Real-world study finds lower weight loss with GLP-1 drugs due to early discontinuation
A Cleveland Clinic study shows that semaglutide and tirzepatide – injectable GLP-1 drugs for obesity – produce smaller weight loss in a real-world setting because

Should AMA ‘Support’ a Registry to Track Side Effects of GLP-1 Drugs?
(MedPage Today) — CHICAGO — Physicians debated the idea of the American Medical Association (AMA) supporting a registry to track adverse events tied to blockbuster

GLP-1 Medications Overtake Traditional Weight-Loss Drugs
The popularity of glucagon-like peptide-1 (GLP-1) receptor agonists continues, with use of tirzepatide and semaglutide surpassing that of traditional weight-lowering medications.

Amplifye debuts enzyme to supercharge protein digestion and unlock new health benefits
Amplifye, a UC Davis spinout led by former Amyris CEO John Melo, has launched its first product: a proprietary enzyme (P24) claimed to optimize protein

Specialty drug utilization grows
In 2024, the cost and utilization of specialty dermatology drugs significantly drove a 7% increase in pharmaceutical costs, according to a June 10 report from

Metsera’s drug shows potential in early clinical trial – statnews.com
Metsera’s drug shows potential in early clinical trial statnews.com Weight-loss newbie Metsera says once-monthly amylin matches GLP-1 efficacy FirstWord Pharma Obesity Startup Metsera Shares Rise on Early-Stage

PSG Releases 2025 Drug Benefit Design Report: PBM Unbundling Gains Momentum and Payers Navigate GLP-1 Coverage Decisions Amid Rising Costs
DALLAS–(BUSINESS WIRE)–Pharmaceutical Strategies Group (“PSG”), an EPIC company, published its 2025 Trends in Drug Benefit Design Report, delivering critical insights into how payers are navigating

Lembas GLP-1 Ingredient Manufacturer Enters The Market Following $3.6 Million Pre-Seed Investment
Lembas is a new b2b ingredient business that makes a peptide powder that targets the GLP-1 hormone for weight loss

Who should be taking weight-loss drugs? Doctors share best candidates
Weight-loss drugs continue to grow in popularity, with market researchers predicting that global demand for the medications could reach $150 billion by 2035. GLP-1 agonists

Real-World GLP-1 Weight-Loss Results Differ From Trials
New findings about semaglutide and tirzepatide use from health records suggest lower overall weight loss but also factors that predict success. Medscape Medical News

Injectable medications for obesity found to produce smaller weight loss in a real-world setting
A Cleveland Clinic study shows that semaglutide and tirzepatide—injectable GLP-1 drugs for obesity—produce smaller weight loss in a real-world setting because patients discontinue treatment or