Oncobesity News Posts

GLP-1s Like Ozempic, Wegovy Linked to Surprising Drop in Violent Behavior
Saturday, June 20 – GLP-1s may help reduce impulsivity, alcohol intake, and violent behaviors in adults. Image Credit: munro/gettyimages
A recent study found that GLP-1 medications like Ozempic and Wegovy may help lower impulsive and violent behaviors.
The researchers noted that higher impulsivity and alcohol use were significantly associated with violent behavior overall, but were weaker among those using GLP-1s.

Weight-loss drugs linked to ‘Ozempic ears’ and other cosmetic complaints, surgeons say
Saturday, June 20 – GLP-1 weight loss drugs like Ozempic are linked to cosmetic concerns, including sagging earlobes, deflated breasts and flatter buttocks, surgeons say.

Ozempic Might Cut Risk Of Broken Bones, Study Says
FRIDAY, June 19, 2026 — Ozempic doesn’t only help people lose weight, but might also protect against broken bones, a new study says.
People with type 2 diabetes treated with semaglutide (Ozempic/Wegovy) had a 15% lower risk of bone…

GLP-1 drugs show early promise for improving fertility in males and females
Friday, June 19 – GLP-1 drugs show early promise for improving fertility in males and females

Mayim Bialik’s GLP-1 Experience Left Her With ‘Uncontrollable’ GI Symptoms
Friday, June 19 – Mayim Bialik recently shared the “nightmare” experience she had after using a GLP-1 drug. Image Credit: Laurent Koffel/Getty Images
Actor Mayim Bialik has shared her “nightmare” experience that left her with weeks of side effects after one GLP-1 medication dose.
Bialik said her symptoms included severe diarrhea and full-body aches.
She revealed that she tried a GLP-1 after her doctor suggested it may help with her autoimmune disease symptoms.

Setting a Goal Weight May Lead to Greater Success With GLP-1s Like Zepbound
Friday, June 19 – Setting a weight loss goal may yield greater success with GLP-1 drugs like Zepbound. Image Credit: Crispin la valiente/GettyImages
A recent study found that people who set personal weight loss targets may achieve greater results with GLP-1 medications.
People using tirzepatide (Zepbound or Mounjaro) saw more weight loss if they set goals or had previously tried structured diet plans.

What’s next for GLP-1 weight loss drugs?
Friday, June 19 – What’s next for GLP-1 weight loss drugs? Alex Hogan explores on the new episode of STATus Report. Watch now.

FDA Approves PTSD Device; GLP-1s for ADHD? Probiotics and Geriatric Depression
Friday, June 19 – (MedPage Today) — The FDA cleared Wave Neuroscience’s biomarker-guided neuromodulation system (MeRT) to treat post-traumatic stress disorder (PTSD), the company announced.
Gastrointestinal interoception was disrupted across multiple domains in…

ENDO: Significant Decrease in Physical Activity Seen After GLP-1 Receptor Agonist Initiation
WEDNESDAY, June 17, 2026 — Adults with obesity initiating glucagon-like peptide-1 receptor agonist (GLP-1RA) medications have a significant decrease in their physical activity, according to a study presented at ENDO 2026, the annual meeting of the…

ENDO: More Than Half of Adults With T2DM Who Discontinue GLP-1 Receptor Agonists Reinitiate Treatment
WEDNESDAY, June 17, 2026 — More than half of adults with type 2 diabetes mellitus (T2DM) who discontinue glucagon-like peptide-1 receptor agonists (GLP-1 RAs) reinitiate within one year, according to a study presented at ENDO 2026, the annual…

Taking a GLP-1 Like Ozempic? These Health Risks Are Higher in the Heat
Wednesday, June 17 – Using GLP-1s may increase your risk of heat-related illnesses. Image Credit: Nora Carol Photography/Getty Images
GLP-1 medications may increase heat-related risks by suppressing thirst and reducing fluid intake.
Thirst reduction may lead to severe dehydration and even kidney damage.
GLP-1 drugs may also lower blood pressure in some people, potentially leading to other heat-related issues in people with low blood pressure.

Ozempic and Wegovy linked to surprising drop in violent behavior
A Rutgers study suggests GLP-1 drugs such as Ozempic and Wegovy may weaken the link between impulsive tendencies and violent behavior. The surprising finding hints that these medications could affect how people act on impulses, though researchers stress that cause and effect have not been proven.

Ozempic users may be making a major weight-loss mistake, new study suggests
Wednesday, June 17 – New research finds GLP-1 users significantly reduced physical activity, with daily steps and exercise declining after starting a weight loss medication.

Lower Risk Of Death, Clots Among Autoimmune Patients Taking GLP-1 Drugs
WEDNESDAY, June 17, 2026 — People with an autoimmune disease and obesity might lower their risk of dangerous blood clots and death by taking Ozempic or Zepbound, a new study says.
Autoimmune diseases like celiac disease, vitiligo, psoriasis…

Beyond GLP-1s: The next chapter of obesity care
Wednesday, June 17 – The rapid rise of GLP-1 medications such as semaglutide and tirzepatide has transformed obesity treatment. Still, experts say medications alone are not enough to address one of the nation’s most pressing chronic diseases.

Tirzepatide outperformed semaglutide weight-loss drug results in real world patients, study shows
Wednesday, June 17 – Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have become popular for weight loss, but results vary from person to person and from drug to drug. Venky Soundararajan and colleagues explored the full range of responses to tirzepatide (e.g., Mounjaro or Zepbound) and semaglutide (e.g., Ozempic, Wegovy or Rybelsus) by analyzing de-identified electronic health records for matched cohorts of 10,339 tirzepatide-treated and 10,339 semaglutide-treated patients. In the real world, outcomes ranged from minimal weight loss to more than a 25% reduction in body weight.

Eli Lilly Settles Mounjaro TM Suit Against Seattle Area Clinics
Wednesday, June 17 – Eli Lilly has agreed to drop a lawsuit accusing two Washington clinics of ripping off its trademarks for the weight loss drugs Mounjaro and Zepbound, according to a voluntary dismissal motion filed in federal court on Monday, almost two weeks after a judge rejected a resolution proposed by the parties.

Medicare’s GLP-1 Program Looms; Chemicals in Breast Milk; Acromegaly Drug Rejected
Wednesday, June 17 – (MedPage Today) — A massive wave of new prescriptions for GLP-1 receptor agonists is expected following the July launch of a Medicare pilot program that offers the drugs for weight loss for a flat $50 monthly copay. (Axios)
Meanwhile, nearly…

ADA: Orforglipron Beneficial for Reducing HbA1c in Type 2 Diabetes
TUESDAY, June 16, 2026 — Orforglipron is beneficial for blood glucose control in individuals with type 2 diabetes using metformin or taking insulin glargine, according to two studies published online June 8 in The Lancet and the Journal of the…

How Lilly is defending its GLP empire
Monday, June 15 – Eli Lilly’s recent GLP-2 deal with Hanmi Pharm is another step in the drugmaker’s quest to grow its GLP franchise beyond weight loss and deepen its push into gastrointestinal disease.

Most people who stop GLP-1 drugs like Ozempic eventually return
Monday, June 15 – Many people prescribed GLP-1 drugs for type 2 diabetes (such as Victoza, Ozempic, or tirzepatide) stop taking them, but a surprising number later return to treatment. Researchers found that newer medications appear to keep patients on therapy longer, while side effects remain a major reason for discontinuation.

Semaglutide (Ozempic) linked to fewer bone fractures despite greater weight loss
Monday, June 15 – A large real-world study suggests semaglutide (Ozempic, Wegovy, Rybelsus) may offer an unexpected bonus for people with type 2 diabetes: stronger protection against bone fractures while delivering greater weight loss. Researchers analyzing health records from nearly 60,000 adults found that people taking semaglutide experienced about 15% fewer fractures than those using other common weight-loss medications, despite losing more weight.

People Walk, Exercise Less After Starting Ozempic, Zepbound
TUESDAY, June 16, 2026 — Folks losing weight on Ozempic or Zepbound tend to start slacking off when it comes to exercise, a new study says.
People’s daily step count and physical activity declined after starting a GLP-1 medication…

Behavioral modifications like goal setting could lead to greater weight loss on tirzepatide
Tuesday, June 16 – One of the largest real-world studies of people taking GLP-1 medications found women, those without pre-existing conditions such as type 2 diabetes and high blood pressure, and behavioral factors such as previously setting a weight goal were the best predictors of total weight loss, according to a study presented at ENDO 2026, the Endocrine Society’s annual meeting in Chicago.

Tirzepatide may change how the body uses energy, trial suggests
Tuesday, June 16 – Tirzepatide doesn’t just help people lose weight; it also activates brown adipose tissue, representing a major milestone in obesity research, according to a study presented at ENDO 2026, the Endocrine Society’s annual meeting in Chicago.

Diabetes Patients on Semaglutide Had Fewer Fractures, Study Finds
Tuesday, June 16 – (MedPage Today) — CHICAGO — The GLP-1 receptor agonist semaglutide (Ozempic, Wegovy) was associated with a 15% lower risk for fractures in adults with type 2 diabetes, a review of medical records found.
In a matched analysis involving more…

Apitegromab Preserves Lean Mass When Combined With Tirzepatide
MONDAY, June 15, 2026 — Selective targeting of myostatin by apitegromab preserves lean mass when combined with tirzepatide, according to a study published online June 8 in Nature Medicine.
Richard E. Pratley, M.D., from the AdventHealth…

ENDO: GLP-1 Receptor Agonists Tied to Higher Hypotension Risk in Patients on BP Meds
MONDAY, June 15, 2026 — Among patients with preexisting hypertension taking antihypertensive medications, glucagon-like peptide-1 receptor agonist (GLP-1 RA) use is associated with an increase in hypotensive-related events, according to a study…

Tirzepatide GLP-1 medication may be most effective for weight loss
Monday, June 15 – GLP-1 medications are marketed to help you lose weight, but one may be better at it than the rest, according to a new meta-analysis from the University of Georgia.

Clinical trials suggest GLP-1s may improve fertility in men with obesity
Monday, June 15 – GLP-1s do not harm male hormones or fertility after long-term use, according to a study being presented Monday at ENDO 2026, the Endocrine Society’s annual meeting in Chicago. In fact, the research team found GLP-1s may improve testosterone levels and sperm quality in men with obesity-related low testosterone, while also addressing the underlying effects of obesity.

GLP-1s may aid bone health as well as weight loss in type 2 diabetes
Tuesday, June 16 – GLP-1s may aid bone health as well as weight loss in type 2 diabetes.

How GLP-1 Weight Fluctuations Are Driving Up Clothing Returns
Monday, June 15 – Popular weight loss drugs, including Ozempic and Wegovy, have already transformed how people shop for food. Now, they’re impacting the way users buy their clothes as they slim down. But with so many shoppers uncertain about their fit and size, retailers are seeing a surge in returns that’s proving to be very costly. NBC’s Emilie Ikeda reports for TODAY.

Many Patients Stop And Restart GLP-1 Meds, Study Finds
MONDAY, June 15, 2026 — Folks are told that once you start taking Ozempic or Zepbound, you’ll need to stay on them to maintain the drugs’ benefits.
But patients prescribed such GLP-1 drugs are more likely to stop them and then…

Taking GLP-1s While On BP Meds May Up Your Risk Of Dizzy Spells, Fainting
MONDAY, June 15, 2026 — Researchers are flagging a potential safety concern tied to GLP-1 medications and blood pressure.
A new Northwestern Medicine study tracked more than 42,000 adults who started semaglutide, tirzepatide or liraglutide…

New GLP-1 diabetes pill delivers major weight loss and blood sugar control
A new oral GLP-1 medication helped people with type 2 diabetes dramatically improve blood sugar control and lose weight in a major clinical trial. The results suggest that highly effective diabetes treatments may soon become available in a much more convenient pill form.

Semaglutide linked to lower bone fracture risk
Tuesday, June 16 – In people with type 2 diabetes, semaglutide was associated with a 15% reduction in bone fractures and greater weight loss compared with other anti-obesity medications, according to a study presented at ENDO 2026, the Endocrine Society’s annual meeting in Chicago.

More than half of those who stop GLP-1s restart within a year, study finds
Tuesday, June 16 – People prescribed GLP-1 medications are more likely to start and stop than most people assume, according to a study presented at ENDO 2026, the Endocrine Society’s annual meeting in Chicago.

People taking GLP-1 weight loss drugs like Ozempic started moving less
Tuesday, June 16 – People taking popular weight-loss drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound may be losing pounds, but they could also be moving less. Researchers analyzing Fitbit data found that daily step counts and exercise levels dropped after people started these medications, despite successful weight loss. Because the drugs can reduce muscle mass along with fat, the decline in physical activity raises concerns about preserving strength and long-term health.

Study finds exercise decreases among people taking GLP-1 medication
Sunday, June 14 – Adults with obesity who lost weight with glucagon-like peptide-1 (GLP-1) receptor agonist medications significantly decreased their physical activity, which is essential to protect muscle, according to a study presented at ENDO 2026, the Endocrine Society’s annual meeting in Chicago.

GLP-1 and SGLT2 Users Face Different Risk for Diabetic Foot Complication
Sunday, June 14 – (MedPage Today) — CHICAGO — Use of GLP-1 receptor agonists was tied to significantly lower risks of major diabetic foot complications compared with SGLT2 inhibitors in adults with type 2 diabetes, a large, real-world analysis indicated.
Compared…