Oncobesity News Posts

The Ozempic and Wegovy mistake sending thousands to poison control

Thursday, July 9 – Poison control calls involving semaglutide (Ozempic and Wegovy) soared after the drug was approved for weight management, with researchers linking the increase to accidental dosing mistakes rather than intentional misuse. Simple education about proper weekly dosing and gradual dose increases could help prevent many of these avoidable incidents.

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Closeup of blue pill in palmx

AstraZeneca’s New Oral GLP-1 Aids Weight Loss and Lowers Blood Sugar

Wednesday, July 8 – AstraZeneca’s new oral GLP-1 pill showed promising results for weight loss and blood sugar in a phase 2 trial. Guido Mieth/Getty Images

A new GLP-1 oral medication from AstraZeneca, known as elecoglipron, lowered blood sugar levels and led to 10.5% weight loss in a phase 2b clinical trial.

Experts say GLP-1 drugs in tablet form may encourage more people to take these medications to help treat type 2 diabetes and obesity.

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New weight loss pill beats oral Ozempic in major trial

Wednesday, July 8 – A new once-daily weight-loss pill called orforglipron delivered better weight loss and blood sugar improvements for people with type 2 diabetes than the leading oral semaglutide in a major clinical trial. The tablet could offer a more convenient alternative to injectable drugs like Ozempic and Wegovy because it doesn’t require refrigeration or special timing with meals. It’s also cheaper to manufacture, which could expand access globally.

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Generic Mounjaro, Zepbound May Be Coming, Rivaling Current GLP-1s

Tuesday, July 7 – Federal regulators have agreed to review a Swiss pharmaceutical company’s applications for two cheaper generic versions of Zepbound and Mounjaro. MK Photo/Alamy Stock Photo

Federal regulators have agreed to review the applications from Swiss pharmaceutical company Sandoz for two cheaper generic versions of the tirzepatide medications Zepbound and Mounjaro.

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Secret Shopper Study Warns About Online GLP-1 Sellers

Tuesday, July 7 – (MedPage Today) — Two-thirds of online GLP-1 receptor agonist sellers did not require speaking with a clinician ahead of a prescription, a secret shopper study revealed.
Out of 49 websites tested, 13 required a video visit and three required…

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Oral GLP-1 Drug May Simplify Diabetes Treatment

Tuesday, July 7 – (MedPage Today) — At the American Diabetes Association annual meeting, results from the ACHIEVE-5 trial showed that adding oral orforglipron (Foundayo) to basal insulin significantly improved glycemic control, reduced body weight, and limited…

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Wegovy weight-loss pill goes on sale on UK high street and online pharmacies

Tuesday, July 7 – Thousands of people begin receiving their first deliveries of once-a-day medication made by Novo Nordisk A once-a-day Wegovy weight-loss pill has gone on sale at high street and online pharmacies in the UK, but is not yet available on the NHS.Thousands of people began receiving their first deliveries of the pill, made by the Danish drugmaker Novo Nordisk, on Monday. It contains the same active GLP-1 ingredient as the Wegovy jab, semaglutide, and is similarly effective, according to studies. Continue reading…

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Twice-Monthly GLP-1 Shot Helps Manage Blood Sugar, Weight Loss in Trial

Saturday, July 4 – A new biweekly GLP-1 injection has been shown to significantly reduce blood sugar in a clinical trial. Image Credit: Hannes P Albert/picture alliance via Getty Images

A new GLP-1 medication demonstrated efficacy in reducing blood sugar in people with type 2 diabetes in a phase 2b clinical trial. 

Bofanglutide is a biweekly (once every 2 weeks) injection compared to once-weekly shots like Ozempic and Wegovy. 

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7 things to know about Medicare’s new GLP-1 coverage

Friday, July 3 – For decades, it’s been against the law for Medicare to pay for weight-loss medication. But that changed on July 1, with the launch of a new program called Bridge. It gives some people over 65, or who have Medicare for other reasons, access to some weight management medications if they meet certain weight and health criteria.

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GLP-1 drugs outperform SGLT-2 drugs for patients with Afib and type 2 diabetes

Thursday, July 2 – Individuals with atrial fibrillation (Afib), or irregular heart rhythm, are at increased risk of stroke, chronic kidney disease and heart failure. These risks are significantly exacerbated if a type 2 diabetes diagnosis is added to the mix, says Md Mohaimenul Islam, Ph.D., research assistant professor in the Department of Pharmacy Practice in the University at Buffalo School of Pharmacy and Pharmaceutical Sciences.

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Medicare to Cover GLP-1 Weight Loss Drugs: What to Know

Wednesday, July 1 – A new pilot program will allow Medicare Part D beneficiaries to access popular weight loss drugs, including Wegovy, Zepbound and Foundayo, at a significantly reduced price for a limited time. NBC News medical contributor Dr. John Torres joins TODAY to break down the details.

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GLP-1s Like Ozempic, Mounjaro Linked to Reduced Stroke, Heart Risks

Tuesday, June 30 – A growing body of evidence shows that GLP-1 drugs benefit cardiovascular health. Image Credit: Healthline/Munro/Getty Images

GLP-1 medications like Ozempic and Wegovy help protect heart health, but stopping the medications may reduce the protective effects.

Some research suggests that GLP-1s containing tirzepatide (Zepbound, Mounjaro) may help lower the risk of further complications in people with cardiovascular disease.

Other research suggests that GLP-1s may help reduce thromboembolic events, such as deep vein thrombosis (DVT), in people with obesity and autoimmune diseases.

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Could one shot replace weekly GLP-1 drugs? DNA approach shows months-long effects in mice

Tuesday, June 30 – Scientists at The Wistar Institute have shown that a single injection of a small, circular piece of genetic instruction can produce weight loss and blood glucose control in murine models that lasts up to 10 times as long as incretin-mimicking drugs like Ozempic and Wegovy. If shown to be successful in clinical trials, this new method of delivery could eliminate the need for repeated dosing, which currently limits patient access and adherence to these therapies.

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Popular GLP-1 weight loss drugs are being misused by people struggling with eating disorders, research reveals

Tuesday, June 30 – Glucagon-like peptide-1 receptor agonists (GLP-1 RAs), such as Ozempic or Wegovy, have revolutionized type 2 diabetes and weight-loss management, but they have also led to some unfortunate outcomes. A recent study in JAMA Psychiatry has raised concerns that GLP-1 medications may be misused by people with eating disorders. These are serious mental health conditions in which thoughts about food, body weight and body shape become overwhelming, leading to harmful eating behaviors and an intense drive to control food intake. Although concerns about weight or appearance are common, eating disorders go far beyond these everyday worries.

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Can GLP-1 Weight Loss Drugs Give Athletes an Unfair Advantage?

Saturday, June 27 – GLP-1 drugs can provide benefits that may boost an athlete’s performance, but do these medications give them the competitive edge? Getty Images/The Good Brigade

Debates are emerging over whether GLP-1 drugs boost athletic performance.

However, experts say the loss of lean mass associated with using these drugs may cancel out any competitive advantages.

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Taste, Smell Disturbances Seen in GLP-1 Users

Saturday, June 27 – (MedPage Today) — Use of GLP-1 receptor agonists was associated with a higher risk of smell and taste disturbances among adults with type 2 diabetes, an analysis of electronic health record (EHR) data suggested.
Compared with matched controls…

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