Friday, October 30 – While many are aware of terms like “Ozempic face” and “Ozempic butt,” people are discovering another “side effect” of GLP-1 medications.View Entire Post ›

Friday, October 30 – “I still don’t see ‘me’ in the mirror.”View Entire Post ›

Friday, October 30 – With the commercial business performing so well, Eli Lilly is eyeing earlier business development bets to build out a longer-term pipeline.

Friday, October 30 – People who regain weight after bariatric surgery may benefit from glucagon-like peptide-1 receptor agonists, commonly called GLP-1 medications, according to a study involving Regenstrief Institute, Indiana University, Purdue University and University of Florida researchers. The study found that patients prescribed these medications lost more of their regained weight over six and 12 months than comparable patients who did not use them.

Friday, October 30 – Eli Lilly’s shares rose 4% in early morning trading after reporting revenue of $24.4 billion, well past consensus estimates.

Thursday, October 29 – Already tagged with a potential “best-in-class” description by industry analysts on the back of positive phase III data unveiled earlier this year, Eli Lilly and Co.’s retatrutide turned up another win, this time besting Novo Nordisk A/S’ GLP-1 blockbuster, Ozempic (semaglutide), on A1C-lowering and weight loss endpoints in a phase III study in patients with type 2 diabetes.

Thursday, October 29 – Eli Lilly announced that its investigational drug retatrutide was more effective at lowering blood sugar and cutting weight than Novo Nordisk’s Ozempic in a large diabetes study.

Thursday, October 29 – Eli Lilly’s next-gen weight loss drug retatrutide soundly beat Novo’s approved medicine Ozempic in weight loss and blood sugar reduction, padding the case for a regulatory application that’s expected in the first quarter of 2027.

Thursday, October 29 – Data add to expectations that the drug will be one of Lilly’s greatest growth drivers. 

Wednesday, October 28 – Law360 Healthcare Authority looks at a Novo Nordisk loss in its challenge to Eli Lilly’s GLP-1 advertising, an Ohio verdict in wrongful death litigation over Johnson & Johnson’s talc baby powder and other legal news from the past week.

Wednesday, October 28 – (MedPage Today) — A U.S. judge rejected Novo Nordisk’s request to temporarily block Eli Lilly from running advertisements claiming its weight-loss and diabetes drugs are more powerful. (Reuters via AOL)
The FDA expanded the approval for insulin…

Wednesday, October 28 – GLP-1 medications have become a popular tool for weight loss. But are they appropriate for all age groups? Short for glucagon-like peptide-1, GLP-1s are medications approved by the Food and Drug Administration that treat type 2 diabetes and now obesity. They work by mimicking a natural hormone in the gut that lowers blood sugar, simulates the feeling of fullness and slows digestion.

Wednesday, October 28 – (MedPage Today) — Menopausal women taking hormone therapy in addition to a GLP-1 medication may see greater and sustained weight loss, a retrospective cohort study suggested.
Women taking semaglutide (Wegovy) and menopausal hormone therapy had…

Tuesday, October 27 – New research shows that using hormone therapy with a GLP-1 during menopause may lead to greater weight loss. Tatsiana Volkava · Moment/Getty

A study presented at the 2026 Annual Meeting of The Menopause Society found that women using menopause hormone therapy (MHT) alongside semaglutide (Ozempic, Wegovy) experienced greater weight loss than those taking semaglutide alone.

Tirzepatide (Mounjaro, Zepbound) combined with MHT showed only modest early differences in weight loss, with no statistically significant difference at later time points.

Certain hormone therapy medications are FDA-approved to treat menopause symptoms such as hot flashes and vaginal dryness, but not for weight loss.

Tuesday, October 27 – A New Jersey federal judge on Monday refused to issue an injunction blocking Eli Lilly & Co. from running ads allegedly comparing its GLP-1 drug to Novo Nordisk Inc.’s using “outdated” clinical trials and “false superiority messages,” ruling that Novo Nordisk hasn’t shown it would be irreparably harmed.

Tuesday, October 27 – (MedPage Today) — Multiple sclerosis (MS) patients exposed to a GLP-1 receptor agonist had lower rates of relapse activity and steroid use, reduced incidence of optic neuritis, and fewer demyelinating events compared with those who didn’t use…

Tuesday, October 27 – (MedPage Today) — During an appointment with her psychiatrist, a 50-year-old woman with bipolar disorder reported new symptoms of tremor in both hands, slurred speech, and blurred vision.
She was taking lithium, but 3 weeks prior, she had also…

Tuesday, October 27 – Ascletis Pharma Inc. has submitted an IND application to the FDA for ASC-39 oral tablets, an oral small-molecule selective amylin receptor agonist, for the treatment of obesity. A phase I trial is expected to begin in the fourth quarter.

Monday, October 26 – After trying diets and GLP-1 medications without lasting weight loss, former competitive weightlifter Dana Bichler (pictured above) lost more than 80 pounds following a minimally invasive procedure. Photo: Dana Bichler

Former competitive weightlifter Dana Bichler lost more than 80 pounds after undergoing endoscopic sleeve gastroplasty (ESG), a minimally invasive weight loss procedure.

After struggling with weight regain despite dieting and trying GLP-1 medications, Bichler pursued ESG amid concerns about his obesity-related fatty liver disease.

Sunday, October 25 – Early research suggests petrelintide may have fewer GI effects than GLP-1.

Sunday, October 25 – Despite the president’s comments, patients say these medications have been life-changing, and their effectiveness cannot be ignored.

Saturday, October 24 – GLP-1 medications such as semaglutide and tirzepatide have changed daily life for millions of people, though side effects are common. Photo by Getty

GLP-1 medications like semaglutide and tirzepatide can lead to significant weight loss and may help reduce inflammation, improve mobility, and quiet persistent thoughts about food. Many people report life changing results after years of unsuccessful diets.

A Healthline story on Mayim Bialik’s GLP-1 side effects became our most engaged Facebook post of the year, as thousands of commenters shared hard side effects and life changing results. Research also increasingly links GLP-1s to benefits beyond weight loss.

Friday, October 23 – New research on GLP-1 drug usage from EY-Parthenon shows that weight loss is now the most popular use of the drug once dedicated to diabetes patients. CBS News’ Megan Cerullo reports on how the drugs are changing spending habits for users.

Friday, October 23 – “I took GLP-1s and was miserable the whole time. I basically felt like I was pregnant.”View Entire Post ›

Friday, October 23 – Early uptake was rapid for oral semaglutide (Wegovy pill) relative to injectable incretin-based weight management therapies, according to a study published online Oct. 13 in Annals of Internal Medicine.

Friday, October 23 – Growing usage of GLP-1 drugs for weight loss is reshaping how consumers shop for food and clothes, according to consulting firm EY-Parthenon.

Friday, October 23 – Someone taking a weight-loss drug might leave half their dinner because they feel comfortably full. They might also stop because they feel nauseous. Measuring the leftovers would reveal the same result, but tell researchers little about why the person stopped eating.

Friday, October 23 – U.S. is poised to issue a proposed rule that would subject outbound licensing deals with Chinese biotech companies to additional scrutiny

Friday, October 23 – As telehealth promotes GLP-1s for addiction, experts worry about fragmented care, and exposing patients to unknown risks.

Thursday, October 22 – Ozempic plus hormone therapy may help boost weight loss at menopause.

Thursday, October 22 – For patients with nonarteritic anterior ischemic optic neuropathy (NAION), glucagon-like peptide-1 (GLP-1) receptor agonist exposure is associated with earlier sequential NAION, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held Oct. 9 to 12 in New Orleans.

Thursday, October 22 – Crude odds ratios suggest an increased risk for age-related macular degeneration (AMD) in association with glucagon-like peptide-1 receptor agonist (GLP-1 RA) use, but this finding is reversed after adjustment for cardiometabolic confounding variables, according to a study presented at the annual meeting of the American Academy of Ophthalmology, held Oct. 9 to 12 in New Orleans.

Thursday, October 22 – (MedPage Today) — A single, 10-minute transcranial ultrasound session led to a modest but significant drop in delusion scores among people with schizophrenia in a sham-controlled pilot trial. (npj Acoustics)
President Trump announced that the…

Thursday, October 22 – Around half a million Australians use GLP-1 medications for diabetes—and when you add people who use them for obesity and weight-related conditions, the total is much higher.

Thursday, October 22 – (MedPage Today) — Treatment with the novel triple agonist retatrutide improved obstructive sleep apnea (OSA) in adults with obesity or overweight regardless of type 2 diabetes, two parallel randomized clinical trials showed.
Mean reduction in…

Wednesday, October 21 – Post hoc analyses in women divided by menopausal status show how Novo’s next-generation GLP-1 drug affects key cohorts of patients.

Wednesday, October 21 – (MedPage Today) — Roughly a quarter of active-duty U.S. Army men had a single morning testosterone concentration under 300 ng/dL, a commonly used cutoff for low testosterone. (JAMA)
Nearly half of American women ages 40 to 60 reported menopausal…

Wednesday, October 21 – The success stories of GLP-1 weight-loss medications are dominating the airwaves. Midlife women, who commonly experience weight gain resulting from menopause, have been especially drawn to the drugs.

Tuesday, October 20 – Mayo Clinic researchers found that GLP-1 receptor agonists, medications widely used for diabetes and weight management, were associated with a lower risk of dialysis or kidney transplantation in adults with bipolar disorder and chronic kidney disease.

Tuesday, October 20 – While GLP-1 medicines have become synonymous with weight loss, at least one expert thinks amylin would have been the go-to target if biopharma had been focused on the blockbuster indication 10 years ago. A new wave of therapies is now exploring this potentially gentler mechanism.