Oncobesity News Posts

GLP-1 Drugs Like Ozempic, Wegovy May Help With Binge Eating Disorder
Saturday, July 18 – GLP-1 medications like Ozempic and Wegovy may help ease symptoms of binge eating disorder and related eating behaviors. Giselleflissak/Getty Images
A new study found that GLP-1RAs could reduce key symptoms of binge eating disorder.
These included binge eating severity, loss of control eating, and emotional eating.
Experts say that GLP-1RAs could potentially augment existing treatments for binge eating disorder, like psychotherapy.

Why GLP-1 Drugs May Raise Muscle Loss, Frailty Risk for People Over 65
Saturday, July 18 – A new report states that older adults using GLP-1 drugs may have a higher risk of loss of muscle mass, malnutrition, dehydration, and other frailty-associated conditions. Getty Images
A new report states that older adults using GLP-1 drugs may have a higher risk of loss of muscle mass, malnutrition, and dehydration.
However, the benefits of taking these drugs should be weighed against these risks when the medications are prescribed.

Semaglutide and other GLP-1 drugs not linked to risk of degenerative eye disease in adults with type 2 diabetes
Saturday, July 18 – An estimated 27% of U.S. adults with diabetes are using glucagon-like peptide-1 receptor agonists (GLP-1 RAs)—a type of medication that mimics the GLP-1 hormone—to lower blood sugar and support weight loss. Some research has suggested that their use can reduce the risk of developing other diseases.

GLP-1 shows promise for patients with advanced fatty liver disease
Saturday, July 18 – Researchers at the University of California San Diego School of Medicine have reported results from a large international clinical trial showing that semaglutide, a medication in the GLP-1 class of drugs widely used to treat diabetes and obesity, may help reduce liver scarring in patients with advanced fatty liver disease, including those with early-stage cirrhosis.

Compounders maintain a firm grip on the GLP-1 market
Saturday, July 18 – Despite an FDA crackdown and numerous pharma lawsuits, nearly 1 in 5 patients are taking cheaper weight-loss alternatives despite the risks.

What Are ‘Ozempic Feet?’ Doctors Explain Latest GLP-1 Side Effect From Weight Loss
Friday, July 17 – Some people using GLP-1 drugs for weight loss have reported changes in their feet. Image Credit: stockvisual/Getty
“Ozempic feet” is the latest anecdotal side effect of GLP-1 drugs for weight loss.
The unusual phenomenon is a result of rapid weight loss, which may cause foot pain, changes in shoe size, and a more bony appearance in the feet.

Study identifies patients with obesity most likely to benefit from GLP-1-based treatment
Friday, July 17 – Why do some people lose substantial weight with GLP-1-based medications while others see more modest results? A Mayo Clinic study offers a potential answer by identifying a distinct biological subtype of obesity that responds especially well to tirzepatide, a medication that mimics two naturally occurring hormones involved in appetite and blood sugar regulation, moving the field closer to precision medicine for obesity.

Rise of GLP-1s raises long-term affordability questions
Friday, July 17 – As use of GLP-1s surged across the U.S., average total payments per user also climbed sharply, according to a new Northwestern University study that analyzed national trends in GLP-1 use and spending between 2017 and 2022. These total payments included out-of-pocket costs paid by patients as well as payments from insurers, employers and government programs.

Ozempic-like drugs have more benefits to the body than just losing weight, meta-analysis shows
Friday, July 17 – A meta-analysis of 10 randomized controlled trials involving more than 23,000 participants, presented at the International Congress on Obesity (ICO 2026), hosted by the World Obesity Federation (WOF) in Mexico City, Mexico (July 15–17), shows that the GLP-1 class of obesity drugs is associated with a marked reduction in systemic inflammation beyond its anti-obesity effects, potentially explaining how the drugs can reduce cardiovascular risk factors.

Eli Lilly invests in Oura to support patients on GLP-1 drugs
Saturday, July 18 – Eli Lilly on Wednesday made an equity investment in wearable ring startup Oura as the drugmaker looks for ways to support patients taking its GLP-1 medications.
An Oura spokesperson declined to share the size of …

Internet searches on weight-loss medications have increased 25-fold since the launch of GLP-1 drugs
Thursday, July 16 – Public interest in obesity medication has risen 25-fold since the launch of GLP-1 receptor agonist drugs, new research presented at the International Congress on Obesity (ICO2026) in Mexico City, Mexico, hosted by the World Obesity Federation (July 15–17) shows.

New GLP-1 Concern; FDA Sued by Health Groups; Over 750 Dead in Ebola Outbreak
Thursday, July 16 – (MedPage Today) — Note that some links may require registration or subscription.
A preprint study flagged signals of frailty in seniors taking the GLP-1 drug tirzepatide (Zepbound) for weight loss. (Reuters via Yahoo!)
The House passed a bill…

GLP-1s Good for Marriage Prospects? RFK Jr.’s Diabetes Ads Axed; CGMs for Toddlers
Thursday, July 16 – (MedPage Today) — GLP-1 drugs did not appear to improve diabetes patients’ job or marriage prospects, according to a working paper from the National Bureau of Economic Research. (Axios)
The U.S. by 2035 will have 57 million overweight individuals…

China’s Mindrank raises $52M series B to advance oral GLP-1
Thursday, July 16 – Mindrank AI Ltd. completed a $52 million series B round to advance MDR-001, its AI-discovered oral small-molecule GLP-1 receptor agonist, which is in phase III trials for obesity in China.

The GLP‑1 disclosure dilemma: Should you tell a date you’re using Ozempic for weight loss?
Wednesday, July 15 – As a Gen Xer who lived through the “heroin chic” years, when skeletal models were celebrated for jutting bones and sallow skin, the recent popularity of the #Y2KSkinny trend fills me with dread.

GLP-1s and Blinding Condition; Cyclosporiasis Source Found? Tylenol-Autism Lawsuits
Wednesday, July 15 – (MedPage Today) — Note that some links may require registration or subscription.
A cohort study found that diabetes patients taking GLP-1 receptor agonists had a higher risk of anterior ischemic optic neuropathy, a potentially blinding eye condition…

Popular weight-loss drugs Ozempic and Wegovy may slow biological aging
Wednesday, July 15 – Researchers found that semaglutide, the active ingredient in Ozempic and Wegovy, slowed biological aging markers in adults with HIV, marking the first clinical evidence that the drug may influence human aging. Although the findings are encouraging, scientists say larger studies are needed before concluding that the medication can help people age more slowly.

Study Dampens Hope for GLP-1s as Insulin Off-Ramp in Type 2 Diabetes
(Wednesday, July 15 – MedPage Today) — Adding a GLP-1 receptor agonist was not associated with a lower likelihood of discontinuing existing basal insulin therapy among veterans with type 2 diabetes compared with other glucose-lowering agents, a target emulation trial…

Can Ozempic prevent cancer? A doctor explains why the headlines are easy to misread
Wednesday, July 15 – In the weeks around the 2026 annual meeting of the American Society of Clinical Oncology, my phone kept buzzing with alerts about GLP-1 drugs and cancer. The headlines were everywhere—from NPR and The Washington Post to Substack and heated exchanges on social media—all circling the same claim: Ozempic might lower the risk of cancer.

China’s Mindrank raises $52M series B to advance oral GLP-1
Wednesday, July 15 – Mindrank AI Ltd. completed a $52 million series B round to advance MDR-001, its AI-discovered oral small-molecule GLP-1 receptor agonist, which is in phase III trials for obesity in China.

How GLP-1 drugs like Ozempic could help prevent lung scarring after COVID
Monday, July 13 – How GLP-1 drugs like Ozempic could help prevent lung scarring after COVID

Forget GLP-1s—GLP-3s show promise in phase 3 weight loss and diabetes trial
Monday, July 13 – Phase 3 clinical trial results (TRANSCEND-T2D-1) published in The Lancet report that retatrutide, an investigational once-weekly injection for diabetes management, can significantly improve blood sugar levels and lead to substantial weight loss in people with Type 2 diabetes. The study included adults with Type 2 diabetes who were not taking diabetes medicines and whose blood sugar was not adequately controlled with diet and exercise alone.

If A GLP-1 Medication Has Changed Your Life For The Better, We Want To Hear About It
Sunday, July 12 – Whether it’s been about weight, blood sugar, PCOS, food noise, or something else entirely, we want to hear.View Entire Post ›

Study Compares GLP-1 Drugs on Their Benefits, Harms
Sunday, July 12 – (MedPage Today) — Variable weight-loss and cardiovascular benefits were seen with GLP-1 drugs in a systematic review and network meta-analysis, but effects on quality of life were less clear.
Across 262 randomized studies published through November…

Newer Diabetes Drugs, Including GLP-1 Agonists, Tied to Autoimmunity Risk
Friday, July 10 – (MedPage Today) — Analysis of hundreds of thousands of patient records showed differing risks for autoimmune disorders for new users of the more recent types of antidiabetic medications.
Rates of new-onset autoimmune conditions were compared…

GLP-1 use hits record high as Medicare opens access to weight-loss drugs
Friday, July 10 – The share of U.S. adults taking GLP-1 medications to lose weight has reached a record 11%.

Societies combine to issue recommendations on use of incretin drugs in obesity therapy
Friday, July 10 – Obesity and dietitian societies have joined forces to issue a new consensus statement on recommendations surrounding the use of obesity drugs for weight loss treatment. The statement, which is published in The Lancet Diabetes & Endocrinology, is led by Dr. Laurence Dobbie of the Department of Population Health Sciences, King’s College London, with an international team of 26 authors.

Medicare prescriptions for Wegovy jumped after approval for heart disease
Friday, July 10 – Medicare prescriptions for Wegovy increased sharply after the program started covering the anti-obesity medication to prevent heart problems, but just a fraction of beneficiaries likely eligible received the treatment, according to new research published in the American Journal of Managed Care by the USC Schaeffer Center for Health Policy & Economics.

GLP-1s and Liver Cancer Recurrence; IBS Acupuncture; Transmural Healing in Crohn’s
Friday, July 10 – (MedPage Today) — Diabetes patients with hepatocellular carcinoma (HCC) experienced longer time to HCC recurrence and longer survival when they initiated a GLP-1 agonist rather than a DPP-4 inhibitor, a target trial emulation study found. (Gut…

The Ozempic and Wegovy mistake sending thousands to poison control
Thursday, July 9 – Poison control calls involving semaglutide (Ozempic and Wegovy) soared after the drug was approved for weight management, with researchers linking the increase to accidental dosing mistakes rather than intentional misuse. Simple education about proper weekly dosing and gradual dose increases could help prevent many of these avoidable incidents.

Record High GLP-1 Use; Intense Interval Exercise; Endometriosis and Androgens
Thursday, July 9 – (MedPage Today) — Americans’ use of GLP-1 injectables for weight loss reached a record high, nearly quadrupling since 2024, according to a national Gallup poll.
For patients with type 2 diabetes and peripheral artery disease, GLP-1 receptor agonists…

Medicare GLP-1 Bridge program may lead to bone problems
Thursday, July 9 – The new Medicare GLP-1 Bridge program offers broader, more affordable access to weight loss drugs to address the growing obesity crisis. But there’s a catch when it comes to bone health.

GLP-1 ‘secret shopper’ study finds gaps in online prescribing
Thursday, July 9 – Getting a GLP-1 prescription online can be quick and convenient, but new research suggests it may come with surprisingly little medical oversight. The findings are published in the journal JAMA.

Hengrui, Kailera’s oral GLP-1 clears late-stage bar in China but US results still pending
Thursday, July 9 – New data on Hengrui Pharma and Kailera Therapeutics’ investigational oral GLP-1 have validated the late-stage weight loss asset and paved the road for a regulatory submission in China, but analysts pointed to high rates of nausea and vomiting that could challenge the ongoing U.S. study.

Survodutide weight-loss drug may reduce harmful fat while preserving muscle
Wednesday, July 8 – Survodutide weight-loss drug may reduce harmful fat while preserving muscle

AstraZeneca’s New Oral GLP-1 Aids Weight Loss and Lowers Blood Sugar
Wednesday, July 8 – AstraZeneca’s new oral GLP-1 pill showed promising results for weight loss and blood sugar in a phase 2 trial. Guido Mieth/Getty Images
A new GLP-1 oral medication from AstraZeneca, known as elecoglipron, lowered blood sugar levels and led to 10.5% weight loss in a phase 2b clinical trial.
Experts say GLP-1 drugs in tablet form may encourage more people to take these medications to help treat type 2 diabetes and obesity.

New weight loss pill beats oral Ozempic in major trial
Wednesday, July 8 – A new once-daily weight-loss pill called orforglipron delivered better weight loss and blood sugar improvements for people with type 2 diabetes than the leading oral semaglutide in a major clinical trial. The tablet could offer a more convenient alternative to injectable drugs like Ozempic and Wegovy because it doesn’t require refrigeration or special timing with meals. It’s also cheaper to manufacture, which could expand access globally.

Generic Mounjaro, Zepbound May Be Coming, Rivaling Current GLP-1s
Tuesday, July 7 – Federal regulators have agreed to review a Swiss pharmaceutical company’s applications for two cheaper generic versions of Zepbound and Mounjaro. MK Photo/Alamy Stock Photo
Federal regulators have agreed to review the applications from Swiss pharmaceutical company Sandoz for two cheaper generic versions of the tirzepatide medications Zepbound and Mounjaro.

Secret Shopper Study Warns About Online GLP-1 Sellers
Tuesday, July 7 – (MedPage Today) — Two-thirds of online GLP-1 receptor agonist sellers did not require speaking with a clinician ahead of a prescription, a secret shopper study revealed.
Out of 49 websites tested, 13 required a video visit and three required…

New CDER appointment elevates longtime GLP-1 reviewer
Tuesday, July 7 – Acting FDA CDER director Michael Davis has promoted a longtime FDA staffer as an acting deputy director at the drug center.
Lisa Yanoff, an agency veteran with expertise in metabolic drug reviews, is taking over …