Oncobesity News Posts

Regulator-mandated study finds no link between semaglutide use and pancreatic cancer

Tuesday, September 29 – New research presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, found no link between semaglutide use and pancreatic cancer in nationwide registry data from Denmark, Sweden and Norway. The regulator-mandated post-authorization study was presented by Anton Pottegård, a professor at the University of Southern Denmark in Odense, and colleagues.

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How much do Americans spend on GLP-1 medications? Medical students measure drug affordability

Tuesday, September 29 – The number of people using GLP-1 treatments like Ozempic and Wegovy for weight loss or chronic conditions has increased rapidly, with more than 1 in 10 U.S. adults currently taking such medications. A new study led by medical students at Virginia Commonwealth University has shed light on how this rise in GLP-1 drug use is affecting Americans’ wallets.

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Does GLP-1 use result in significant hair loss?

Monday, September 28 – Experts share what you need to know about GLP-1-related hair loss as the side-effect gets more attention from researchers About 20 million people across the US, UK, and EU are taking GLP-1 receptor agonists like tirzepatide and semaglutide (Ozempic or Mounjaro are common brands) for weight loss and type 2 diabetes. As their use has surged, we’re learning more about their side-effects. One that’s been getting a lot of attention from researchers lately: hair loss.In one survey of people who take these medications, 20% of respondents experienced hair shedding, although the lack of high-quality data from a randomized, controlled trial to assess this side-effect makes it difficult to know exactly how common it is. Continue reading…

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Daily oral GLP-1 medication linked to similar weight loss across three menopausal stages

Sunday, September 27 – New analyses to be presented at the annual meeting of the European Association for the Study of Diabetes (EASD) in Milan, Italy, Sept. 28–Oct. 2, show that orforglipron, a daily oral medication for weight loss and type 2 diabetes, was associated with similar weight loss among women of different ages and at different life stages: before, during and after menopause.

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Zepbound and Mounjaro may turn on the body’s calorie-burning brown fat

Sunday, September 27 – Tirzepatide, sold as Mounjaro and Zepbound, activated calorie-burning brown fat in obese mice, revealing a potential metabolic effect beyond appetite suppression. If confirmed in humans, the finding could help explain the drug’s powerful benefits and inspire more comprehensive treatments for obesity and diabetes.

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GIPC1 inhibitor exhibits preclinical efficacy in pancreatic ductal adenocarcinoma

Saturday, September 26 – Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a reported 5-year survival rate of approximately 13.3%, largely because of late diagnosis, rapid progression and resistance to treatment. GAIP-interacting protein C terminus 1 (GIPC1), overexpressed in PDAC, is a scaffolding protein that stabilizes multiple oncogenic receptors and signaling complexes involved in proliferation, survival, adhesion, migration and chemoresistance.

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Mylan Wants Del. Judge To Clear Wegovy Generic Drug

Friday, September 25 – Mylan Pharmaceuticals Inc. has launched a lawsuit in Delaware federal court asking for a finding that its proposed generic version of Novo Nordisk Inc.’s blockbuster weight loss drug Wegovy does not infringe a patent, the latest salvo in a larger intellectual property fight over the GLP-1.

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GLP-1 weight loss and diabetes drugs linked to nutritional deficiencies in nearly 1 in 6 children

Friday, September 25 – Children taking GLP-1 medications (such as Victoza, Saxenda, Trulicity, and Ozempic) for weight loss, prediabetes, or type 2 diabetes may face an overlooked risk: nutritional deficiencies. A new study found that nearly 1 in 6 young patients developed a diagnosed deficiency within a year of starting treatment, with vitamin D deficiency affecting about 12%.

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FDA Warns Pharmacy About Illegal GLP-1 Compounding

Thursday, September 24 – (MedPage Today) — The FDA issued a warning letter this month to Empower Pharmacy over its mass production of compounded GLP-1 weight-loss and diabetes drugs, citing illegal copycat manufacturing and insanitary conditions.
Following a facility…

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Expert Tips for Thriving While on GLP-1 Medications

Wednesday, September 23 – Heidi Skolnik, a sports nutritionist, exercise physiologist and bestselling author, joins TODAY to discuss her latest book, “Your GLP-1 Game Plan,” that is filled with guidance on what to eat and how to move and thrive on weight loss medications. “The medication doesn’t give you nourishment, and it doesn’t give you strength. You really need to go beyond the scale to think about your ‘why.’ And we know that when you focus on health beyond appearance, you do better,” she says.

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Hundreds of lawsuits filed against some GLP-1 Makers over vision loss

Tuesday. September 22 – Hundreds of Americans are suing GLP-1 drugmakers Novo Nordisk and Ely Lilly, saying they were not adequately warned of the potential danger of vision loss. In statements, Novo Nordisk says, in part, they are “vigorously” fighting the lawsuits, saying they are “without merit,” while Eli Lilly says in part, it maintains “patient safety” is its “top priority.” NBC News’ Stephanie Gosk has the story.

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GLP-1s linked to nutritional deficiencies in children

Tuesday. September 22 – Children prescribed GLP-1 medications for weight loss, prediabetes or type 2 diabetes are at risk for nutritional deficiencies—diagnosed in nearly one in six patients (16.8%) within the first year—according to a new study published in the journal Childhood Obesity. Vitamin D deficiency was the most common, identified in 12.4% of children within one year of GLP-1 treatment.

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Stopping Ozempic may raise heart attack and stroke risk

Tuesday, September 22 – A large study suggests the cardiovascular benefits of GLP-1 drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound can disappear surprisingly quickly when treatment stops. After two years off the medications, patients had a 22% higher risk of heart attack, stroke, and death compared with those who stayed on them.

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Microdosing GLP-1s Like Wegovy, Zepbound May Still Lead to Weight Loss

Saturday, September 19 – Research shows that microdosing GLP-1 medications may still lead to weight loss. Tatsiana Volkava · Moment/Getty

Recent research suggests that people may still lose weight while staying on the lowest starting doses of GLP-1 medications, such as Wegovy or Zepbound, for longer periods.

After one year, people taking sustained low dose tirzepatide lost about 5.5% of their body weight, while those taking sustained low dose semaglutide lost about 2.2%.

Lower doses were associated with more modest weight loss than higher doses, but sustained low dose semaglutide was also associated with lower rates of some side effects.

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Ozempic can change your body. Can it change your life?

Saturday, September 19 – Ozempic and other GLP-1 medications can improve blood sugar, weight, and cardiovascular health, but researchers found little evidence that they also improve mental health, employment, marriage, or overall well-being. The findings suggest the drugs’ broader life effects may be subtler than their dramatic physical health benefits.

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Parties Clash Over Scope Of GIPA In DNA Test-Taker’s Suit

An Illinois federal judge is weighing whether the state’s genetic privacy law protects against disclosing information about people who have taken genetic tests, with a DNA testing company accused of unlawfully sharing such information with Google arguing Wednesday the statute applies only to disclosure of actual test results.

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Preserving Muscle During GLP-1 Weight Loss

Tuesday, September 15 – (MedPage Today) — Blockbuster GLP-1 receptor agonists revolutionized obesity management in recent years, driving weight loss of up to 20%.
This weight loss, however, can carry a notable downside: Studies estimate that 15% to 40% of GLP-1-induced…

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AI uncovers hidden Ozempic side effects across 400,000 Reddit posts

AI analysis of 400,000 Reddit posts found that users of drugs such as Ozempic, Wegovy, Mounjaro, and Zepbound reported unexpected symptoms including menstrual changes, chills, hot flashes, and fatigue. Researchers cannot say the medications caused these problems, but the patterns may reveal overlooked signals worth studying.

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