Oncobesity News Posts

Genentech Announces Positive Phase II Results for Its Dual GLP-1/GIP Receptor Agonist CT-388 in People Living With Obesity
SOUTH SAN FRANCISCO, Calif.–(BUSINESS WIRE)–Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today positive topline results from CT388-103, a Phase
[Ad hoc announcement pursuant to Art. 53 LR] Roche announces positive Phase II results for its dual GLP-1/GIP receptor agonist CT-388 in people living with obesity
A once-weekly subcutaneous injection of CT-388 achieved a statistically significant placebo-adjusted weight loss of 22.5% (p < 0.001) at 48 weeks at the highest dose

Cipla plans deeper push in domestic market and chronic therapies over next 2–3 years
Cipla’s incoming MD and CEO-designate, Achin Gupta, outlined a two-to-three-year strategy focusing on deepening the domestic market presence and pursuing selective inorganic growth and innovation.

罗氏实验性肥胖症药物在II期临床试验中取得积极结果
Roche”s experimental obesity drug delivers positive phase II results (www.reuters.com) 15:03

Can Diabetes And Obesity Drugs Help Treat Psychiatric Disorders?
A recent study highlights a surprising potential benefit of diabetes and obesity drugs, GLP-1 receptor agonists, in improving overall health and possibly extending survival in

Patients Microdose GLP-1s Without Clinician Input
A larger percentage of GLP-1 users say social media and online research are their most trusted source for microdosing information over their clinician. Medscape Medical

Comparative effectiveness of pharmacotherapy for heart failure with preserved ejection fraction: A systematic review and network meta‐analysis
Abstract Aim Heart failure with preserved ejection fraction (HFpEF) presents a therapeutic challenge, characterised by a paucity of validated treatments. Emerging data suggest that targeting

Amanda Bynes looks unrecognizable as she shows off weight loss after Ozempic admission
CHILD star Amanda Bynes looks slimmer than ever in a new video after revealing she has been using weight loss jabs. At the end of

Pfizer’s CEO on leading after a moonshot—and making deals with Trump
In today’s CEO Daily: Fortune Editor-in-Chief Alyson Shontell interviews Pfizer CEO Albert Bourla. The big story: Target’s incoming CEO speaks out about the immigration crackdown

GLP-1 drugs don’t work for everyone. But personalized obesity care in the future might
As doctors learn why GLP-1s don’t work for about 50% of people, they are also learning more about the complex drivers of obesity. They foresee

Roche sees GLP1/GIP drug from Carmot produce 22.5% weight loss, readies phase 3 trial
Roche’s dual GLP-1/GIP receptor agonist has been tied to 22.5% weight loss at 48 weeks, validating the company’s decision to move the asset into phase

Havas’ GLP-1 Consultancy takes center stage at 1 Billion Followers Summit in Dubai
As GLP-1 adoption accelerates across the Middle East, Havas brings a unique specialized strategic cultural lens to the rapidly evolving metabolic economy

Baseline Therapeutics Launches to Advance GLP-1RA Phase 3 Program in Alcohol Use Disorder
SAN FRANCISCO–(BUSINESS WIRE)– #SUD–Baseline Therapeutics, Inc. (“Baseline”), a clinical-stage biotechnology company developing addiction therapeutics, today announced the launch of the company to advance a new


STAT+: Pharmalittle: We’re reading about a Roche obesity drug, a clash over 340B claims data, and more
Hello, everyone, and how are you today? We are just fine, thank you, despite the frigid temperature and cold winds wafting across the Pharmalot campus,

Women On Menopause Hormone Therapy Lose More Weight With Zepbound, Study Finds
TUESDAY, Jan. 27, 2026 — Good news for women taking hormone therapy for menopause: You might find that weight-loss drugs are more effective.Women on hormone therapy lost 35% more weight while taking Zepbound (tirzepatide), researchers recently r…

STAT+: Roche moves obesity drug to pivotal trials after mid-stage success
Roche plans to launch Phase 3 studies of its leading obesity candidate this quarter after reporting Tuesday that the drug led to significant weight loss

One-shot weight loss: Can gene therapy actually replace the GLP-1 revolution?
Gene therapy for weight loss is being explored as a potential game-changer, with therapy aiming to program the body to produce its own GLP-1 hormone

Why exercise is essential for restoring fitness after GLP-1-based weight loss
This randomized controlled trial shows that structured moderate-to-vigorous exercise, alone or combined with liraglutide, improves physical function and cardiorespiratory fitness after diet-induced weight loss in

The future GLP-1 might be a gene therapy: Report
As GLP-1 pills for weight loss enter the U.S. market, some pharmaceutical companies are testing the possibility of a gene therapy to stimulate GLP-1 production,

Menopause Hormone Therapy May Boost GLP-1 Drug Benefits
(MedPage Today) — Postmenopausal women on the GLP-1 medication tirzepatide (Zepbound) for obesity lost more weight if they were also using menopause hormone therapy, a

Effects of Retatrutide on Learning and Memory in Streptozotocin-Induced Diabetic Rats
Diabetes Mellitus (DM) is a rapidly increasing disease around the world. It is known that DM is associated with numerous complications which affect life quality

Novo Nordisk Faces Class Claims Over GLP-1 Patent Tactics
A South Carolina drug company has launched a proposed class action against major pharmaceutical company Novo Nordisk, alleging it engaged in anticompetitive behavior to prolong

How LIR Life Sciences is making GLP-1 therapy easier to access worldwide
This content was created by Hive Labs in partnership with Fairfax Partners on behalf of LIR Life Sciences Corp. Treating obesity isn’t always as simple

STAT+: Hospital group wants Trump administration to block a new Lilly policy on 340B claims data
The American Hospital Association is asking the Trump administration to stop Eli Lilly from enacting a new policy that would require all hospitals that participate

The 5 Worst Things You Can Do While Taking a GLP-1 for Weight Loss
According to doctors, making a misstep is easier than you may think.
Endocrinologist-Designed AI Nutrition App Launches to Bring Clarity to Eating in the GLP-1 Era
Developed by board-certified endocrinologist Dr. Eiriny Eskander, Caloria delivers physician-backed insights for people managing GLP-1 use, diabetes, PCOS, and menopause. LOS ANGELES, Jan. 26, 2026

Data Shows GLP-1 Drugs Subtly Shift Cravings Toward Real Food
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SGLT2 Inhibitors Linked to Lower Neuropathy Risk
Danish national registry data suggest adults with type 2 diabetes taking SGLT2 inhibitors have a slightly lower risk of developing diabetic foot problems than those

Ozempic boom collides with America’s eating habits as restaurants shrink portions
Once known for bottomless breadsticks and supersized meals, American chain restaurants are increasingly rethinking their portion sizes. As GLP-1 weight-loss medications like Ozempic, Wegovy and

STAT+: Launch of Wegovy pill looks to be going strong so far
Want to stay on top of the science and politics driving biotech today? Sign up to get our biotech newsletter in your inbox. Morning! Today, we see

GLP‐1RAs versus metformin and Parkinson’s risk in type 2 diabetes
Abstract Background Parkinson’s disease (PD) is an increasingly prevalent neurodegenerative condition, particularly among individuals with type 2 diabetes mellitus (T2DM). While prior studies have suggested

Viking Therapeutics, Inc. (VKTX) Advances Obesity Drug Development and Expands Metabolic Disease Pipeline
Viking Therapeutics, Inc. (NASDAQ:VKTX) is one of the best US stocks to buy under $50. On January 12, Viking Therapeutics, Inc. (NASDAQ:VKTX) announced a significant

As GLP-1s become more available, some who aren’t overweight may consider using them
As GLP-1 drugs become more available, some people might use them despite not having excess weight.

Gene therapy for weight loss: Can one shot replace lifelong GLP-1 drugs?
US biotech firm Fractyl Health is developing Rejuva, an experimental gene therapy that aims to trigger long-term weight loss by programming the pancreas to produce

The Microbiome Doctor: Doctors Were Wrong! The 3 Foods You Should Eat For Perfect Gut Health!
World-leading gut health expert PROFESSOR TIM SPECTOR reveals brand new research around why dementia, depression, and anxiety may start in the gut, how flossing lowers

New role for GLP-1 drugs: Improving survival in people with severe psychiatric disorders
This editorial argues that GLP-1 receptor agonists could substantially improve healthspan and reduce premature mortality in people with serious mental illnesses by targeting cardiometabolic risk

GLP-1 Therapy May Offer Added Benefit in IBD Beyond Weight Loss
(MedPage Today) — LAS VEGAS — GLP-1-based therapies may offer benefits in inflammatory bowel disease (IBD) that extend beyond their metabolic indication, according to two

Engineering Marker‐Free Lettuce Chloroplast Genome to Express Functional Glucagon‐Like Peptide‐1 Receptor Agonists Exenatide and Lixisenatide
Engineering of marker-free lettuce chloroplast genome to express CTB-Exenatide and CTB-Lixisenatide for oral delivery. Upper panel: Chemically synthesised exenatide or lixisenatide require expensive production, purification,

Five ways weight-loss jabs are changing spending habits – BBC
Five ways weight-loss jabs are changing spending habits BBC Smaller portions, more protein: How GLP-1s are quietly changing chain restaurant menus NBC News Gut-friendly foods: GLP-1 drives