Oncobesity News Posts

Novo Nordisk (NVO) Fell Following a Profit Warning Release
Parnassus Investments, an investment management firm, released its “Parnassus Value Equity Fund” third-quarter 2025 investor letter. A copy of the letter can be downloaded here.

Neovascular Age-Related Macular Degeneration and GLP-1 RAs—Reply
In Reply We read the letters with great interest commenting on our recent article. We agree that surveillance bias is a concern in observational studies

Neovascular Age-Related Macular Degeneration and GLP-1 RAs
To the Editor A recent article by Shor et al reported a doubling (adjusted hazard ratio, 2.21; 95% CI, 1.65-2.96) in the risk of neovascular

Neovascular Age-Related Macular Degeneration and GLP-1 RAs
To the Editor We read with interest the cohort study by Shor et al evaluating glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and incident neovascular age-related

Neovascular Age-Related Macular Degeneration and GLP-1 RAs
To the Editor We read the recent report on glucagon-like peptide-1 receptor agonists (GLP-1 RAs) and incident neovascular age-related macular degeneration (nAMD) with interest. Given

Neovascular Age-Related Macular Degeneration and GLP-1 RAs
To the Editor We read with interest the study by Shor et al showing a 2-fold relative risk of newly diagnosed neovascular age-related macular degeneration

Rise of Direct-to-Patient GLP-1 Sales Shakes Up Care Models, HCPs Split on Pharma’s Expanding Role
NEW YORK–(BUSINESS WIRE)–The 43rd Barometer from Sermo, a fast, frictionless HCP social engagement platform and leader in healthcare insights, shows that pharma-led direct-to-patient (DTP) GLP-1

Better Buy in 2026: Pfizer or Eli Lilly?
Key Points Eli Lilly has been a dominant force in the GLP-1 market, and that looks set to continue. Pfizer’s acquisitions haven’t paid off yet

More GLP-1s aim to enter US market
Novo Nordisk is seeking FDA approval for an experimental obesity shot, CagriSema (cagrilintide and semaglutide), according to a Dec. 18 news release from the Denmark-based

Can Higher-Dose Wegovy Help Novo Nordisk Regain Obesity Market Share?
Novo Nordisk NVO is a leading player in the obesity market, driven by its blockbuster GLP-1 therapy Wegovy (semaglutide). However, despite being a core growth driver,

STAT+: Pharmalittle: We’re reading about Lilly’s obesity pill, pharma deals with Trump, and much more
Top of the morning to you, and a fine one it is. Clear blue skies and pleasant breezes are enveloping the Pharmalot campus, where the

Mazdutide versus placebo in Chinese adults with type 2 diabetes – Nature
Mazdutide versus placebo in Chinese adults with type 2 diabetes Nature Nature | Two Phase 3 Clinical Results of Mazdutide (GLP-1/GCG Dual Receptor Agonist) in Chinese

How weight-loss jabs are changing the way we eat
Babybel, the “small, ready-to-eat industrial cheese wrapped in its signature red wax”, is an unexpected beneficiary of anti-obesity drugs, said Le Monde. Its French-owned producer

Biomedicines, Vol. 13, Pages 3117: Multimodal Prehabilitation for Hernia Repair: Linking Metabolic Modulation and Mechanical Methods
Biomedicines, Vol. 13, Pages 3117: Multimodal Prehabilitation for Hernia Repair: Linking Metabolic Modulation and Mechanical Methods Biomedicines doi: 10.3390/biomedicines13123117 Authors: Dan Nicolae Paduraru Alexandru Cosmin

Lilly’s orforglipron helped people maintain weight loss after switching from injectable incretins to oral GLP-1 therapy in first-of-its-kind Phase 3 trial – Eli Lilly
Lilly’s orforglipron helped people maintain weight loss after switching from injectable incretins to oral GLP-1 therapy in first-of-its-kind Phase 3 trial Eli Lilly Eli Lilly says

Healthy Returns: 2026 will be the year of obesity pills from Novo Nordisk, Eli Lilly – CNBC
Healthy Returns: 2026 will be the year of obesity pills from Novo Nordisk, Eli Lilly CNBC Novo Nordisk files for FDA approval of CagriSema, the first

Eli Lilly says obesity pill helps maintain weight loss after patients switch from Wegovy, Zepbound – CNBC
Eli Lilly says obesity pill helps maintain weight loss after patients switch from Wegovy, Zepbound CNBC Lilly’s orforglipron helped people maintain weight loss after switching from

2025 in Review: The wellness paradox and the path to healthspan
In 2025, the wellness industry faced contradictions as consumers claimed healthy lifestyles but their use of gut-disrupting drugs told a different story. Despite this, there

Better Buy in 2026: Novo Nordisk or Intuitive Surgical?
Key Points Novo Nordisk’s new indications for semaglutide and its attractive pipeline could allow it to bounce back. Intuitive Surgical should remain the leader in

Eli Lilly Scores Another Major Win: Time to Buy?
Can anyone stop Eli Lilly (NYSE: LLY)? The pharmaceutical leader has established itself as the leader in the fast-growing weight loss market. And although many

Novo Nordisk files for FDA approval of CagriSema, the first once-weekly combination of GLP‑1 and amylin analogues for weight management
CagriSema 2.4 mg/2.4 mg is an investigational fixed-dose injectable medicine that combines the novel amylin analogue, cagrilintide, with semaglutide to target complementary obesity-related pathways1,2 In

Chiptole launches 4-ounce bowl of meat for the Ozempic age
The move signals that we’re about to see a lot more GLP-1-centric menus. Chipotle is officially in its Ozempic era.

Study finds 40% of GLP-1 prescriptions go unfilled: Is cost curbing use of weight loss drugs?
Popular new anti-obesity medications can help people lose 10% to 20% of their body weight, yet a new study indicates that about 40% of those

Lilly’s orforglipron is the first oral obesity therapy to show its worth in the maintenance setting
Eli Lilly’s experimental obesity pill allowed patients who had lost weight on injected GLP-1-based drugs to keep most of the weight off for another year,

Lilly’s orforglipron helped people maintain weight loss after switching from injectable incretins to oral GLP-1 therapy in first-of-its-kind Phase 3 trial
In ATTAIN-MAINTAIN, orforglipron achieved the primary and all key secondary endpoints for weight maintenance vs. placebo at 52 weeks following weight loss on Wegovy or

Mitochondrial control of fuel switching via carnitine biosynthesis
Metabolic adaptation to environmental changes, such as fasting and cold exposure, involves a dynamic shift in fuel utilization from glucose to fatty acid oxidation, a

Eli Lilly says obesity pill helps maintain weight loss after patients switch from Wegovy, Zepbound
Eli Lilly also said it has filed for Food and Drug Administration approval of the daily GLP-1 pill, called orforglipron, for obesity.

STAT+: Eli Lilly’s obesity pill helped patients maintain weight loss after switch from injections
Eli Lilly’s investigational obesity pill largely helped patients maintain their weight loss after they switched from the potent injectable treatments Wegovy and Zepbound, the company

Better Pharmaceutical Buy: Eli Lilly vs. Novo Nordisk
Key Points These two healthcare stocks are top names to invest in, but they haven’t both been doing well of late. Eli Lilly has generated

STAT+: Employers drop coverage for weight loss drugs as pharma’s direct-to-consumer programs grow
When HCA Healthcare, one of the largest hospital systems in the U.S., recently told employees it would stop covering blockbuster obesity drugs Zepbound and Wegovy

Beyond Weight Loss: GLP-1s Show Promise in Breast Cancer
A growing body of evidence suggests GLP-1 receptor agonists may improve survival as well as reduce chemotherapy-related toxicities in women with breast cancer. Medscape Medical

IJMS, Vol. 26, Pages 12163: GLP-1 Signalling as a Therapeutic Avenue in Parkinson’s Disease: A Comprehensive Review
IJMS, Vol. 26, Pages 12163: GLP-1 Signalling as a Therapeutic Avenue in Parkinson’s Disease: A Comprehensive Review International Journal of Molecular Sciences doi: 10.3390/ijms262412163 Authors:

Recent articles on GLP-1 receptor agonists have presented as part of secondary analyses an effect,trial-product estimand, that may be unfamiliar.
submitted by /u/Accurate_Cry_8937 [link] [comments]

Nature | Two Phase 3 Clinical Results of Mazdutide (GLP-1/GCG Dual Receptor Agonist) in Chinese Adults with Type 2 Diabetes Have Been Back-to-Back Published in Nature
SAN FRANCISCO and SUZHOU, China, Dec. 17, 2025 /PRNewswire/ — Innovent Biologics, Inc. (“Innovent”) (HKEX: 01801), a world-class biopharmaceutical company that develops, manufactures and commercializes

Tirzepatide Matches Competitor’s Cardioprotective Benefits for Diabetics
(MedPage Today) — The dual GIP/GLP-1 receptor agonist tirzepatide (Mounjaro, Zepbound) was just as cardioprotective as the GLP-1 drug dulaglutide (Trulicity) in patients with type

Weight Watchers Launches New GLP-1 Program and AI App Features
What You Should Know: – Weight Watchers has unveiled a massive platform overhaul integrating GLP-1 prescription management with a redesigned app featuring an AI body

Is cost curbing use of weight loss drugs?
Anna Sinaiko. Stephanie Mitchell/Harvard Staff Photographer Health Is cost curbing use of weight loss drugs? 40 percent of GLP-1 prescriptions go unfilled, study finds Alvin

GLP-1 drugs move from healthcare story to broader market debate
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GLP-1 Receptor Agonist Use May Lower Vertebral Fracture Risk With Type 2 Diabetes
WEDNESDAY, Dec. 17, 2025 — Glucagon-like peptide 1 receptor agonists (GLP-1 RAs) may protect against vertebral fractures in people with diabetes, according to a research

US health insurance premiums rose nearly 3x the rate of worker earnings over the past 25 years
Vivian Ho and Salpy Kanimian in The Conversation: Some of the premium increases can be attributed to an increase in hospital outpatient visits and coverage of GLP-1 drugs.