Oncobesity News Posts

Lilly Prepares $1B+ Orforglipron Stock Ahead of Approval as Novo Brings Wegovy Pill Overseas
Eli Lilly has long been gearing up for the launch of orforglipron, announcing as early as February 2024 that it was ramping up manufacturing investments for the weight-loss pill.

STAT+: Trump administration is urged to use a federal law to authorize generic versions of GLP-1 drugs
Public Citizen contends that Novo Nordisk and Eli Lilly’s obesity drugs are straining budgets so much that generics should be authorized.

Potentially Blinding Eye Condition Tied to Ozempic Again
(MedPage Today) — Risk for a rare, potentially blinding eye condition was low, but it was significantly higher in diabetes patients who started semaglutide (Ozempic) versus SGLT2 inhibitors, an observational study of U.S. veterans showed.
Among…

Novo Nordisk to expand Irish factory for Wegovy pill
Novo Nordisk is ramping up its footprint in Ireland with a planned expansion of its Athlone factory to make its Wegovy pill, the company confirmed to Endpoints News.
The Athlone site will supply the pill …

Viking to push oral GLP-1/GIP drug into phase III obesity trial
Viking Therapeutics Inc. said after-market hours Feb. 11 that it plans to advance its oral dual GLP-1/GIP receptor, VK-2735, into a phase III trial for obesity in the third quarter of 2026. VK-2735 is a novel dual glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide (GLP-1/GIP) receptor agonist.

How employers feel about the state of healthcare (and GLP-1s)
A few weeks back, I moderated a dinner conversation among company heads of HR and benefits here in Denver organized by primary care operator Marathon Health.
These employee benefit leaders are a group I hear …

Using GLP-1s to maintain a normal weight? There are benefits and risks
Drugs like Zepbound and Wegovy are intended for people who are overweight. Some patients are using them after bariatric surgery to keep pounds from creeping back. Others may just want to lose a few pounds.

Oral Wegovy Brings in Thousands of New GLP-1 Patients
The oral version of Wegovy has made GLP-1 medicines more accessible and acceptable to many patients who had steered clear of injectable versions, healthcare analytics firm Truveta suggests.

More Good News for GLP-1 Agonists and Cancer Risk
(MedPage Today) — Women with nonmalignant uterine disease and a history of GLP-1 agonist and progestin treatment had a significantly lower risk of endometrial cancer (EC) compared with progestins alone, a retrospective study showed.
Based on…

Ascletis raises $107M to advance oral GLP-1 to phase III trials
Ascletis Pharma Inc. raised HK$843.53 million (US107.93 million) in a placement on the Hong Kong Stock Exchange to advance its lead program, ASC-30, a small-molecule glucagon-like peptide-1 (GLP-1) receptor agonist that can be dosed once monthly subcutaneously and once daily orally for treating obesity.

Blockbuster weight loss drugs like Ozempic deliver big results but face big questions
Three major reviews commissioned by the World Health Organization find that GLP-1 drugs including tirzepatide (sold as Mounjaro and Zepbound), semaglutide (Ozempic and Wegovy), and liraglutide (Victoza and Saxenda) can lead to substantial weight loss in people with obesity. But while the results are impressive, researchers caution that most trials were funded by drugmakers, long term safety data are still limited, and side effects such as nausea are common.

Secondary Cardiovascular Disease Prevention With Semaglutide at Cash Price Is Cost-Effective
TUESDAY, Feb. 10, 2026 — Lowering the annual cost of semaglutide by 18 percent (from $8,604 to $7,055) or making the current cash price available to all patients would make semaglutide cost-effective, according to a study published online Feb. 4…

Hims & Hers Wegovy Knock-Off Pill Sparks Lawsuit After FDA Crackdown
Hims & Hers has withdrawn its low cost compounded weight loss pill after pressure from top U.S. health officials and a major lawsuit. Image courtesy of Novo Nordisk
Hims & Hers recently announced a $49 compounded semaglutide pill, offering a low cost alternative to the new Wegovy pill.
However, the compounded version was withdrawn from the market after pressure from the HHS and FDA.

Ozempic Pill Launching; Glucose Monitor Makers Warned; Thyroidectomy in Older Adults
(MedPage Today) — The FDA approved three doses — 1.5 mg, 4 mg, and 9 mg — of a new oral semaglutide formulation for diabetes (Ozempic tablets), Novo Nordisk announced.
An ad for Novo Nordisk’s weight loss pill version of semaglutide (Wegovy…

US FDA finds ad introducing Wegovy pill misleading
Novo Nordisk A/S’ television ad introducing the tablet form of its weight-loss drug, Wegovy (semaglutide), to American consumers didn’t pass regulatory muster.

GLP-1 drugs may protect the heart beyond weight loss, trial results suggest
With the use of GLP-1 medications on the rise, cardiologists are seeing benefits to heart health, and it might not all be related to weight loss alone. GLP-1 medications, including semaglutide, are a class of drugs that act on receptors throughout the body, influencing insulin sensitivity, appetite regulation, inflammation and metabolic health. These therapies traditionally were used to treat diabetes; however, weight loss is a well-recognized side effect, and they are now used for weight loss goals.

Kailera, Hengrui Push Oral GLP-1/GIP Pill to Phase 3 After Clearing Mid-Stage China Study
Kailera will launch a global Phase 2 study of ribupatide this year, while Hengrui will push the asset into Phase 3 in China.

New Novo Nordisk weight-loss drug more effective than Wegovy in clinical trial

Hims Pulls Cheaper Wegovy Pill After Federal Scrutiny
MONDAY, Feb. 9, 2026 — Hims & Hers says it will stop selling a low-cost copy of a new weight-loss pill made by Novo Nordisk, after federal officials raised concerns that the product may violate drug laws.
The online health company…

Novo Sues Hims & Hers Over Compounded Version of Oral Wegovy Pill
Novo Nordisk has sued Hims for allegedly violating patents protecting semaglutide, seeking potentially “hundreds of millions” in damages, John Kuckelman, the pharma’s general counsel, said. The wellness platform pulled its version of the drug just days after launching it.

Novo Nordisk sues Hims over Wegovy patent infringement, considers seeking ‘hundreds of millions’ in damages
Novo Nordisk on Monday said it is suing telehealth company Hims & Hers for allegedly infringing its patent on the weight loss medication semaglutide — not just for the pill version but also for the injectable …

STAT+: Novo Nordisk sues Hims & Hers for infringing on a key Wegovy patent
Novo Nordisk sues Hims & Hers for infringing on a key Wegovy patent.

Can Ozempic Cure Addiction?
GLP-1 drugs, which have helped some people curb drug and alcohol use, may unlock a pathway to moderation.

What is ‘food noise’? UK surgeon explains why people with obesity are more reactive to food; shares 5 ways to curb it
“Food noise” is a real thing where some brains experience heightened reward sensitivity associated with food. Dr Rajan explains how GLP-1 treatment can help.

Summary of JP Morgan Conference in Obesity and Metabolic Diseases
Here’s a summary of the major announcements and trends from the 44th Annual JP Morgan Healthcare Conference in San Francisco (January 12–15, 2026) specifically in

Day 1 @ JP Morgan in Obesity Drugs and Therapies
JP Morgan 2026: Obesity & GLP-1 Therapies Take Center StageWhat the Latest Deals and Data Mean for the Future of Metabolic MedicineThe J.P. Morgan Healthcare

Day 2 @ JP Morgan in Obesity Drugs and Therapies
Here are the **highlights from Day 2 of the JP Morgan Healthcare Conference (San Francisco) specifically related to obesity, weight-gain therapies, and related drug developments

Cardiologist explains benefits of GLP-1 drugs go beyond just weight loss: ‘Future of how we treat heart, liver…’
Everyone’s talking about weight loss drugs like Ozempic, Wegovy and Mounjaro and their implications on weight loss – but their benefits go way beyond that.

JP Morgan Healthcare Conference – Day 3 Highlights (Obesity & Metabolic Therapies)
JP Morgan Healthcare Conference – Day 3 Highlights (Obesity & Metabolic Therapies)1. Shift From “Weight Loss” to Chronic Metabolic DiseaseDay 3 discussions made it clear

Cardiologist with 20 years of experience shares the truth behind GLP-1 drugs and weight loss: ‘Disaster always follows…’
Dr Bhojraj explains that GLP-1 isn’t a medication but a natural hormone, and while it can help, they have side effects and aren’t meant for

Does Ozempic need to be taken forever once started? UK surgeon explains the effects of stopping GLP-1 drugs
According to Dr Rajan, GLP-1 drugs such as Ozempic is not designed for long-term weight loss, which requires a comprehensive approach.

Is ozempic forever? UK surgeon explains how GLP-1 drugs work, and whether you need to take them indefinitely
If you are considering GLP-1 drugs for weight loss, it might be a more serious commitment than you expected. Dr Rajan explains how they work.

Struggling with chronic stress? Wellness coach shares 7 nutrients to lower cortisol and boost GLP-1 naturally
Chronic stress not only makes you feel overwhelmed but can also deplete key nutrients and mess with hormones. Rachel shares 7 nutrients that can help.

Urgent warning issued for Ozempic after GLP-1 drugs linked to suicide
New precautions added for GLP-1 drugs as reports of mood changes and contraceptive concerns emerge in Australia.

Cardiovascular benefits of GLP-1 drugs independent of weight loss
Revising our earlier interpretation of SELECT trial data in light of new analyses The post Cardiovascular benefits of GLP-1 drugs independent of weight loss appeared

Itching at the GLP-1 site of injection
Some people will get itching at the site of injection of the GLP-1 drugs. This is not common but is irritating. There are some things you can do to lessen the severity of the reaction.

Trump Cuts Prices on Ozempic and Wegovy in Deal With GLP-1 Weight Loss Drug Makers
President Trump’s plan drops the price of Ozempic and Wegovy for Americans, with plans for Medicare to cover the popular GLP-1 weight loss drugs.

EASO Framework for Pharmacological Obesity Treatment – Sick Fat vs. Fat Mass
A framework published by the European Association for the Study of Obesity (EASO) that addresses the pharmacological treatment of obesity and its complications. This framework proposes a new

Surgery beats Ozempic for long-term health, Cleveland Clinic finds
Weight-loss surgery dramatically outperformed GLP-1 medications in improving longevity and reducing heart, kidney, and eye complications for people with obesity and diabetes. Over 10 years, patients lost far more weight and required fewer medications. Experts say surgery continues to offer survival advantages even in the age of potent obesity drugs.

💪 The HIV and Weight Loss Drugs Connection – GLP-1 Agonists in HIV Management
The provided source explores the increasing use of GLP-1 receptor agonists like semaglutide and liraglutide in individuals with HIV. It highlights that these medications are beneficial for addressing obesity