Oncobesity News Posts

Weight-loss drug no silver bullet for Alzheimer’s as big trial fails
Scientists have failed to show that weight-loss wonder drug semaglutide slows the progress of Alzheimer’s disease (AD), as two-year clinical trials end in disappointment for

GLP-1 discontinuation associated with more weight gain and pregnancy complications
In a study led by researchers at Mass General Brigham, pregnant individuals who stopped taking popular weight loss GLP-1 medications before or early in their

Study links GLP-1 use to some pregnancy risks — but the study has key caveats
A new study hints that pregnant people who have previously taken drugs like Ozempic may face a higher risk of certain poor pregnancy outcomes. But

Ozempic Drug Fails to Quell Alzheimer’s in Novo Nordisk Trials – The New York Times
Ozempic Drug Fails to Quell Alzheimer’s in Novo Nordisk Trials The New York Times Semaglutide fails to slow progression of Alzheimer’s in highly anticipated trials, Novo

What are The Economist’s predictions for 2026?
PHOTO ART: MERCA2.0 The Economist published its traditional end-of-year special edition, The World Ahead 2026, an in-depth analysis projecting the key themes and trends that

Ozempic Drug Fails to Quell Alzheimer’s in Novo Nordisk Trials
The studies were a significant setback for the optimistic view that semaglutide and other GLP-1 drugs could help prevent a number of brain diseases.

Popular obesity drug fails in hotly anticipated Alzheimer’s trials
The studies may still hold clues to the powers and limits of GLP-1 drugs

The complicated relationship between GLP-1s and pregnancy – The Washington Post
The complicated relationship between GLP-1s and pregnancy The Washington Post Patients who discontinue GLP-1s found to have more weight gain, complications during pregnancy Medical Xpress New Moms’

There’s still hope GLP-1 drugs could slow the second-biggest type of dementia
Can GLP-1s treat vascular dementia? One study failed, but some researchers are holding out hope.

Highly Anticipated Alzheimer’s Trials Yield Disappointing Results for GLP-1 Drug
(MedPage Today) — The oral GLP-1 receptor agonist semaglutide (Rybelsus) did not slow Alzheimer’s disease progression in the highly awaited EVOKE phase III trials, Novo
What Comes Back When Stopping GLP-1s?
We knew the weight would return, but what happens to the other benefits when patients are no longer taking GLP-1 drugs? Medscape

Stopping GLP-1s for Pregnancy Linked to Weight Gain, Complications
(MedPage Today) — The recommended discontinuation of GLP-1 receptor agonists during pregnancy was associated with more gestational weight gain and higher risks of pregnancy complications,

Study finds GLP-1 drug might help curb obsessive food cravings
Researchers say a woman struggling with obesity who couldn’t resist eating fatty foods experienced declines in her cravings after taking tirzepatide.

GLP-1 Pill Fails to Slow Alzheimer’s Progression in Clinical Trial
Top-line results from two large clinical trials by Novo Nordisk, the company behind Ozempic and Wegovy, found oral semaglutide failed to slow down Alzheimer’s progression

Alcohol And Fructose, Tangled (and Untangled?)
This paper advances a metabolic hypothesis that I certainly didn’t see coming. One of the great mysteries about alcoholism/alcohol use disorder is its underlying biochemical

GLP-1s Are a Miracle, Let’s Not Ruin It
GLP-1s are helping Americans live better, but Washington has major work to do on safety. A lot has been happening this fall with the rocket ship rise

Obesity Jab Drug Fails To Slow Alzheimer’s
Drug maker Novo Nordisk says semaglutide, the active ingredient for the weight loss jab Wegovy, does not slow Alzheimer’s — despite initial hopes that it

New Moms’ GLP-1 Prescriptions Jumped After Wegovy Approval
(MedPage Today) — Prescriptions for GLP-1 receptor agonists increased among postpartum women once semaglutide (Ozempic, Wegovy) was approved for weight loss, a Danish epidemiological study

Novo Nordisk has a lot of challenges next year and beyond, says Guggenheim’s Seamus Fernandez
Seamus Fernandez, Guggenheim biotech analyst, joins ‘Power Lunch’ to discuss Novo Nordisk’s latest earnings results, if there’s a clear winner in the GLP-1 space and

Patients who discontinue GLP-1s found to have more weight gain, complications during pregnancy
In a study led by researchers at Mass General Brigham, pregnant individuals who stopped taking popular weight loss GLP-1 medications before or early in their

Passing on the pie? Thanksgiving takes a turn in the Ozempic er
Many people using GLP-1 weight loss drugs are seeing big changes during the holiday season. These medicines make people feel full faster, so Thanksgiving meals

This Healthcare Company Just Touched $1 Trillion in Market Cap. Should You Invest $1,000?
Key Points Eli Lilly has a dominant share of the huge and expanding GLP-1 drug market. Its GLP-1 drugs will soon be partially covered by

Monday links: speculating on a bubble
Strategy Investor behavior matters a lot when it comes to investing in ‘oddball funds.’ (morningstar.com) Bubbles are only obvious in hindsight. (ritholtz.com) Crypto How the

Evoke Phase 3 Oral Semaglutide Trials Did Not Demonstrate a Statistically Significant Reduction in Alzheimer’s Disease Progression
Bagsværd, Denmark, 24 November 2025 – Novo Nordisk today announced the top-line results from the 2-year primary analysis of evoke and evoke+ phase 3 trials in early-stage symptomatic Alzheimer’s disease. The two trials were…

Semaglutide improves biomarkers but fails to preserve memory in Alzheimer’s patients
Two major clinical trials evaluating the potential of the weight-loss drug semaglutide to treat Alzheimer’s disease have concluded without showing the desired clinical benefit. The

Lessons Learned From Antiobesity Medication Withdrawal Trials
The use of glucagon-like peptide (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonists, such as tirzepatide, continues to climb amidst patient demand and a growing

Novo Nordisk’s GLP-1 misses goal in closely watched Alzheimer’s trials
The studies offer perhaps the most concrete rebuttal yet to an idea that GLP-1 drugs, which have profound benefits on weight loss and heart health, might

Guiding Obstetric Care and Treatment Decisions for Women With Prior GLP-1 Receptor Agonist Use
Glucagon-like peptide-1 receptor agonists (GLP-1RAs), such as liraglutide and semaglutide, have revolutionized treatment of obesity. Obesity and obesity-related comorbidities increase the risks of adverse outcomes

Increasing Postpartum Use of GLP-1 Receptor Agonists
This study uses data from the Danish Medical Birth Register to examine postpartum use of glucagon-like peptide 1 receptor agonists.

Gestational Weight Gain and Pregnancy Outcomes After GLP-1 Receptor Agonist Discontinuation
This cohort study examines gestational weight gain and pregnancy outcomes after glucagon-like peptide-1 (GLP-1) receptor agonist discontinuation.

Telehealth companies push GLP-1s beyond approved use
Telehealth companies are promoting GLP-1 medications such as Ozempic and Wegovy for cosmetic weight loss in non-obese patients, despite FDA limitations on their approved use,

Will NVO’s U.S. Price Cuts Boost Access & Revive Semaglutide Demand?
Last week, Novo Nordisk NVO announced that its popular semaglutide-based GLP-1 injections, Wegovy (for obesity) and Ozempic (for diabetes), will be offered at a limited-time

Eli Lilly 1st pharma company to reach $1 trillion market cap
Indianapolis-based Eli Lilly is the first publicly traded U.S. healthcare company to reach market capitalization over $1 trillion, elevating the drugmaker to an exclusive list

Readout of Phase 3 Semaglutide Trials Marks Critical Moment in Alzheimer’s Research and Suggests Potential for Combination Therapies
Data provides new insights into targeting the diverse pathobiology of Alzheimer’s disease, an approach spearheaded by the ADDF NEW YORK, Nov. 24, 2025 /PRNewswire/ —

Novo Nordisk Shares Slump After Ozempic Pill Fails in Alzheimer’s Trials – The Wall Street Journal
Novo Nordisk Shares Slump After Ozempic Pill Fails in Alzheimer’s Trials The Wall Street JournalView Full Coverage on Google News

Women who give up weight-loss jabs for pregnancy can suffer harmful weight gain
When women taking weight loss jabs stop their use because of pregnancy, the rebound weight gain brings health risks for their babies. Women who paused

New fat jab warning as pregnancy risks revealed, even after stopping use – from ‘premature birth to extra weight gain’
FAT jabs could harm mum and baby if taken too close to pregnancy, a study suggests. Women who used the GLP-1 injections, such as Wegovy

Ozempic Pill Flops in Major Trials for Alzheimer’s
An oral version of the GLP-1 drug semaglutide failed to significantly slow the disease’s progression compared to a placebo.

The complicated relationship between GLP-1s and pregnancy
A new study sheds light on the risks and benefits of taking GLP-1 weight-loss drugs before having a baby.

People who stop using Mounjaro tend to regain weight and lose other health benefits, says study
Improvements such as reduced ‘bad’ cholesterol and lower blood pressure go into reverse upon stopping weight-loss jabsPeople who stop using the weight-loss jab Mounjaro not only tend to regain weight, but experience a reversal in other health improvements too, research suggests.Mounjaro, which contains the active ingredient tirzepatide, has become a popular medication for weight loss, with studies suggesting that it can help people lose an average of 20% of their body weight after 72 weeks of treatment. Continue reading…