Oncobesity News Posts

AbbVie Announces Positive Topline Results from a Phase 1 Multiple Ascending Dose Study of ABBV-295, a Long-Acting Amylin Analog, in Adults
NORTH CHICAGO, Ill., March 9, 2026 /PRNewswire/ — AbbVie (NYSE: ABBV) today announced positive topline results1 from the multiple ascending dose (MAD) part of its Phase 1 study evaluating the safety, tolerability, pharmacokinetics (PK), and…

Novo Nordisk Expands U.S. Patient Access to FDA-Approved Semaglutide Medicines Through Hims & Hers in Response to a Shift in Their U.S. GLP-1 Business Model
Plainsboro, NJ, US and Bagsværd, Denmark, 09 March 2026 – Novo Nordisk today announced it has reached an agreement with telehealth company Hims & Hers that will take effect later this month. Under the terms of the agreement, Hims…

Novo Nordisk Ends Lawsuit, Collaborates With Hims & Hers to Sell Semaglutide
(MedPage Today) — Novo Nordisk is dismissing its patent infringement lawsuit against telehealth company Hims & Hers, as the two companies have reached an agreement that will see branded semaglutide (Ozempic, Wegovy) products sold through the…

GLP-1 Drugs and Bone Injury; ‘Fire-Breathing’ Teen Trend; Saunas’ Health Benefits?
(MedPage Today) — Note that some links may require registration or subscription.
GLP-1 receptor agonists may increase the risk of bone and tendon injuries along with conditions such as osteoporosis and gout, a retrospective study suggested. …

Some patients keep weight off with fewer GLP-1 injections, study finds
Some patients taking popular GLP-1 weight loss drugs may be able to keep the weight off while taking injections less often, according to a small new study.

Trial suggests GLP-1 combo therapy cuts fat while preserving muscle in obesity
A recent research study found that a combination of the GLP-1 receptor agonist semaglutide and bimagrumab, an antibody that blocks activin signaling pathways, results in greater weight loss while also preserving lean mass, such as skeletal muscle and connective tissue. In the paper “Bimagrumab and semaglutide alone or in combination for the treatment of obesity: a phase 2 randomized clinical trial,” published Monday in the journal Nature Medicine, Dr. Steven Heymsfield of Pennington Biomedical Research Center describes the results of the BELIEVE study, which showed that the therapy combination addressed lean mass loss associated with GLP-1-based therapies.

GLP-1 Drugs May Prevent, Treat Multiple Addictions
(MedPage Today) — Initiation of a GLP-1 receptor agonist was tied to lower risks of several substance use disorders (SUDs) in adults with type 2 diabetes, according to a target trial emulation using data on veterans.
In patients without a history…

Genentech Announces Positive Phase II Results for Petrelintide, an Amylin Analog Developed for People Living With Overweight and Obesity
South San Francisco, CA — March 5, 2026 — Genentech, a member of the Roche Group (SIX: RO, ROG; OTCQX: RHHBY), announced today positive topline results from the Phase II ZUPREME-1 trial evaluating investigational petrelintide versus placebo in 493…

GLP-1s could help curb substance use disorders, from alcohol to opioids, study suggests
Evidence continues to mount suggesting that GLP-1 drugs like Ozempic and Wegovy may help people cut back on cigarettes, drinking and opioid use disorders and addiction.

Quitting GLP-1 drugs triggers rapid regain, but 25% of weight loss may last
A year after stopping taking weight-loss drugs such as Ozempic and Wegovy, people regain—on average—60% of their lost weight. But beyond this, their regained weight plateaus, with individuals managing to keep off 25% of the weight lost to treatment, say researchers at the University of Cambridge. The work appears in eClinicalMedicine.

No more weekly injections? How lettuce cells could deliver GLP-1 pills
Research led by Penn Dental’s Henry Daniell investigates the use of a lettuce-based, plant-encapsulated delivery platform as a new oral delivery of two GLP-1 drugs previously approved by the FDA in injectable form.

GLP-1 weight-loss drugs comparably effective across age, race and starting weight
Popular GLP-1 receptor agonist drugs for weight loss, also known as GLP-1 RAs, appear to be similarly effective among patients of different ages, races, and starting weights, with women benefiting somewhat more than men, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

What is ‘food noise’? UK surgeon explains why people with obesity are more reactive to food; shares 5 ways to curb it
“Food noise” is a real thing where some brains experience heightened reward sensitivity associated with food. Dr Rajan explains how GLP-1 treatment can help.

Summary of JP Morgan Conference in Obesity and Metabolic Diseases
Here’s a summary of the major announcements and trends from the 44th Annual JP Morgan Healthcare Conference in San Francisco (January 12–15, 2026) specifically in

Day 1 @ JP Morgan in Obesity Drugs and Therapies
JP Morgan 2026: Obesity & GLP-1 Therapies Take Center StageWhat the Latest Deals and Data Mean for the Future of Metabolic MedicineThe J.P. Morgan Healthcare

Day 2 @ JP Morgan in Obesity Drugs and Therapies
Here are the **highlights from Day 2 of the JP Morgan Healthcare Conference (San Francisco) specifically related to obesity, weight-gain therapies, and related drug developments

Cardiologist explains benefits of GLP-1 drugs go beyond just weight loss: ‘Future of how we treat heart, liver…’
Everyone’s talking about weight loss drugs like Ozempic, Wegovy and Mounjaro and their implications on weight loss – but their benefits go way beyond that.

JP Morgan Healthcare Conference – Day 3 Highlights (Obesity & Metabolic Therapies)
JP Morgan Healthcare Conference – Day 3 Highlights (Obesity & Metabolic Therapies)1. Shift From “Weight Loss” to Chronic Metabolic DiseaseDay 3 discussions made it clear

Cardiologist with 20 years of experience shares the truth behind GLP-1 drugs and weight loss: ‘Disaster always follows…’
Dr Bhojraj explains that GLP-1 isn’t a medication but a natural hormone, and while it can help, they have side effects and aren’t meant for

Does Ozempic need to be taken forever once started? UK surgeon explains the effects of stopping GLP-1 drugs
According to Dr Rajan, GLP-1 drugs such as Ozempic is not designed for long-term weight loss, which requires a comprehensive approach.

Is ozempic forever? UK surgeon explains how GLP-1 drugs work, and whether you need to take them indefinitely
If you are considering GLP-1 drugs for weight loss, it might be a more serious commitment than you expected. Dr Rajan explains how they work.

Struggling with chronic stress? Wellness coach shares 7 nutrients to lower cortisol and boost GLP-1 naturally
Chronic stress not only makes you feel overwhelmed but can also deplete key nutrients and mess with hormones. Rachel shares 7 nutrients that can help.

Urgent warning issued for Ozempic after GLP-1 drugs linked to suicide
New precautions added for GLP-1 drugs as reports of mood changes and contraceptive concerns emerge in Australia.

Cardiovascular benefits of GLP-1 drugs independent of weight loss
Revising our earlier interpretation of SELECT trial data in light of new analyses The post Cardiovascular benefits of GLP-1 drugs independent of weight loss appeared

Itching at the GLP-1 site of injection
Some people will get itching at the site of injection of the GLP-1 drugs. This is not common but is irritating. There are some things you can do to lessen the severity of the reaction.

Trump Cuts Prices on Ozempic and Wegovy in Deal With GLP-1 Weight Loss Drug Makers
President Trump’s plan drops the price of Ozempic and Wegovy for Americans, with plans for Medicare to cover the popular GLP-1 weight loss drugs.

EASO Framework for Pharmacological Obesity Treatment – Sick Fat vs. Fat Mass
A framework published by the European Association for the Study of Obesity (EASO) that addresses the pharmacological treatment of obesity and its complications. This framework proposes a new

Surgery beats Ozempic for long-term health, Cleveland Clinic finds
Weight-loss surgery dramatically outperformed GLP-1 medications in improving longevity and reducing heart, kidney, and eye complications for people with obesity and diabetes. Over 10 years, patients lost far more weight and required fewer medications. Experts say surgery continues to offer survival advantages even in the age of potent obesity drugs.

💪 The HIV and Weight Loss Drugs Connection – GLP-1 Agonists in HIV Management
The provided source explores the increasing use of GLP-1 receptor agonists like semaglutide and liraglutide in individuals with HIV. It highlights that these medications are beneficial for addressing obesity

💲 Medicare’s Weight Loss Drug Experiment: Costs & Coverage
A Washington Post article talks about the Trump administration experiment to expand Medicare and Medicaid coverage for GLP-1 weight loss drugs like Ozempic, potentially benefiting millions of Americans

Where is GLP-1 is produced and where in the body does it act?
The provided text describes glucagon-like peptide-1 (GLP-1), detailing its production and the wide array of organs and systems it affects. Primarily, GLP-1 is generated in the intestinal

⚖️ GLP-1s: Integrating Diet and Activity for Optimal Outcomes
This JAMA article provides comprehensive guidance for clinicians on integrating diet and physical activity when prescribing GLP-1 receptor agonists for weight management. It outlines strategies for monitoring and

⚖️ Navigating GLP-1 Weight Loss: Diet, Exercise, and Well-being
This patient-focused guide from JAMA Internal Medicine provides essential information for individuals utilizing GLP-1 medications for weight loss. It outlines the medications’ functions and offers practical dietary advice through a “MEAL” plan, emphasizing muscle

🧪 Unregulated Additives in Compounded GLP-1 Medications
The practice of compounding pharmacies adding various supplements to GLP-1 receptor agonist formulations like semaglutide or tirzepatide is very common in the United States. These additions, which

⚠️ FDA Failures and GLP-1 Compounding Risks
“FDA Regulatory Failures in Enforcing Limits on GLP-1 Compounding Puts Patients at Risk,” critically examines the Food and Drug Administration’s (FDA) oversight of compounded GLP-1 medications.

🤢 Adiposity and Colorectal Cancer Risk: A Systematic Review
A systematic review investigating the relationship between adiposity measures and the risk of developing colorectal cancer (CRC), building upon existing research that often relies solely on Body Mass

💪 GLP-1s: Diabetes, Weight Loss, and Cancer Reduction
This source explores the impact of semaglutide, a weight loss medication, on muscle mass, glucose regulation, and bone health in adults with obesity. It highlights

💲 Tirzepatide: A Cost-Effective Path to Obesity Management
This academic article presents a cost-effectiveness analysis of tirzepatide, a medication for managing overweight and obesity, comparing it against lifestyle modification (LSM) alone. Researchers used a simulation model to project lifetime health

🏃 Physical Activity Trajectories and Mortality: A Meta-Analysis
A systematic review and meta-analysis of 85 prospective studies, examining the long-term impact of physical activity (PA) patterns throughout adulthood on mortality. The authors aimed to understand how consistent, increasing,

Hormone Therapy Enhances Tirzepatide Weight Loss in Menopause
The source discusses research indicating that postmenopausal women on hormone therapy (HT) experience significantly greater weight loss when treated with tirzepatide, an obesity medication, compared